Protein Alignment Sox14 and Sox15

DIOPT Version :9

• Sequence 1: NP_001286801.1
• Gene: Sox14 / 37822
• FlyBaseID: FBgn0005612
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_033261.1
• Gene: Sox15 / 20670
• MGIID: 98363
• Length: 231
• Species: Mus musculus
• Alignment Length: 218
• Identity: 66/218 - (30%)
• Similarity: 111/218 - (50%)
• Gaps: 40/218 - (18%)

  Fly   169 SSTPYSDATRTKKHSPG--------HIKRPMNAFMVWSQMERRKICERTPDLHNAEISKELGRRW 225
            :|.|.....:....|||        .:|||||||||||.::||::.::.|.:||:||||.||.:|
Mouse    21 ASLPLGPQEQEAGGSPGASGGLPLEKVKRPMNAFMVWSSVQRRQMAQQNPKMHNSEISKRLGAQW 85

  Fly   226 QLLSKDDKQPYIIEAEKLRKLHMIEYPNYKYRPQKK-QTRSPGSLKPNQDADGCEARNDTTNNNN 289
            :||..::|:|::.||::||..|:.:||:|||||::| :..|.||:..:|:..|
Mouse    86 KLLGDEEKRPFVEEAKRLRARHLRDYPDYKYRPRRKSKNSSTGSVPFSQEGGG------------ 138

  Fly   290 SLTTLAING-------TTTAGRKS------KRSTSTCQSGSASKRLRNDSGDTSSKPKYEVKMES 341
                ||..|       |||.|.:.      ..||:.......|...|.::....:.|:.:.:::.
Mouse   139 ----LACGGSHWGPGYTTTQGSRGFGYQPPNYSTAYLPGSYTSSHCRPEAPLPCTFPQSDPRLQG 199

  Fly   342 AEQLNSADIILPSADNLISYQSS 364
            ..:.:.:..:.|  |:...|.:|
Mouse   200 ELRPSFSPYLSP--DSSTPYNTS 220

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox14	NP_001286801.1	SOX-TCF_HMG-box	186..257	CDD:238684	36/70 (51%)
Sox15	NP_033261.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..45		5/23 (22%)
		Required to promote HAND1 transcriptional activator activity. /evidence=ECO:0000269|PubMed:16759287	1..45		5/23 (22%)
		SOX-TCF_HMG-box	46..117	CDD:238684	36/70 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	111..136		12/24 (50%)
		Interaction with FHL3. /evidence=ECO:0000269|PubMed:17363903	136..181		11/60 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	186..231		5/37 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838592
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.840