Protein Alignment Sox14 and Sox13

DIOPT Version :10

• Sequence 1: NP_476894.1
• Gene: Sox14 / 37822
• FlyBaseID: FBgn0005612
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: XP_011246247.1
• Gene: Sox13 / 20668
• MGIID: 98361
• Length: 621
• Species: Mus musculus
• Alignment Length: 474
• Identity: 123/474 - (25%)
• Similarity: 179/474 - (37%)
• Gaps: 141/474 - (29%)

  Fly     5 PNQATTEPPLSL--RPGTVPTVPATTPARPATITIQRRHPAPKADSTPHTLPPFSPSPS-PASSP 66
            |.|....||..:  |.|.....|...|.:|..:|.:     ||....|:|    |.||| ..:|.
Mouse   263 PLQLLHSPPAPVVKRSGVAAHHPLQEPPQPLNLTAK-----PKVPELPNT----SSSPSLKMNSC 318

  Fly    67 SPAPAQTPGAQKTQSQAAITHPAAVASPSAPVA--AAAPKTPKTPEPRSTHTHTHTHSQHFSP-- 127
            .|.||         |..|.|.....:.||.|:.  .......|..:......|:|:.:...||
Mouse   319 GPRPA---------SHGAPTRDLQSSPPSLPLGFLGEGDAVTKAIQDARQLLHSHSGALENSPNT 374

  Fly   128 PPRESEMDGERSPS---------HSGHEMTLSMDGIDSSLVFGSARVPVNSSTPYSDATRTKKHS 183
            |.|:..:..:.||:         |...|..||.| :|.|..|..:|   |||
Mouse   375 PFRKDLISLDSSPAKERLEESCVHPLEEAMLSCD-MDGSRHFSESR---NSS------------- 422

  Fly   184 PGHIKRPMNAFMVWSQMERRKICERTPDLHNAEISKELGRRWQLLSKDDKQPYIIEAEKLRKLHM 248
              ||||||||||||::.|||||.:..||:||:.|||.||.||:.::..:||||..|..:|.:.|:
Mouse   423 --HIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARLSRQHL 485

  Fly   249 IEYPNYKYRPQKKQTRSPGSLKPNQDADGCEARNDTTNNNNSLTTLAINGTTTAGRKSKRSTSTC 313
            .:||:|||:|:.|:|              |                .:.|......:.|....|.
Mouse   486 EKYPDYKYKPRPKRT--------------C----------------VVEGRRLRVGEYKALMRTR 520

  Fly   314 QSGSASKRLRNDSGDTSSKPKYEVKMESAEQLNSADIILPSADNLISYQSSEYLPLSTLSNADCD 378
            :.|              ::..|.:..::.:...|:||:.|.|..         |||:.
Mouse   521 RQG--------------ARQSYTIPPQAGQAQVSSDILFPRAAG---------LPLAR------- 555

  Fly   379 EKLHSELSSGPLESRENLSEVVNRFLPLFLGGNEDSQLGVSSL------TQSQHNQSDPTAGLMD 437
                      ||         |..:.|..|..|....:...||      |..:|:.:|   |.|.
Mouse   556 ----------PL---------VEHYDPQGLDPNMPVIINTCSLREEGEGTDDRHSVAD---GEMY 598

  Fly   438 NISDISPINDREELTEEVM 456
            ..|:.......|:..||::
Mouse   599 RYSEDEDSEGDEKSDEELV 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox14	NP_476894.1	HMG-box_SoxC	186..261	CDD:438838	41/74 (55%)
Sox13	XP_011246247.1	HMG-box_SoxD	423..499	CDD:438839	41/75 (55%)