Protein Alignment Sox14 and sem-2

DIOPT Version :10

• Sequence 1: NP_476894.1
• Gene: Sox14 / 37822
• FlyBaseID: FBgn0005612
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_740846.1
• Gene: sem-2 / 172162
• WormBaseID: WBGene00004771
• Length: 404
• Species: Caenorhabditis elegans
• Alignment Length: 487
• Identity: 125/487 - (25%)
• Similarity: 188/487 - (38%)
• Gaps: 157/487 - (32%)

  Fly    50 PHTLPPF---SPSPSPASSPSPAPAQTPGAQKTQSQAAITHPAAVASPSAPVAAAAPKTPKTPEP 111
            ||.:||.   :.:.:.|||.|.|...|.......||....||...|:..
 Worm    17 PHMMPPINWAAAAIAVASSTSGATNATSSNSVATSQQLQHHPYGTAAGG---------------- 65

  Fly   112 RSTHTHTHTHSQHFSPPPRESEMDGERSPSHSGHEMTLSMDGIDSSLVFGSARVPVNSSTPYSDA 176
                   :.|:|...|                                        .|.||||||
 Worm    66 -------YKHAQQAIP----------------------------------------KSVTPYSDA 83

  Fly   177 TRTKKHSPGHIKRPMNAFMVWSQMERRKICERTPDLHNAEISKELGRRWQLLSKDDKQPYIIEAE 241
            |..|| |..||||||||||||||||||||||..||:|||||||:||.||:.|:.::|.|::.|||
 Worm    84 TNCKK-SSNHIKRPMNAFMVWSQMERRKICEHQPDMHNAEISKQLGSRWRSLTDEEKAPFVAEAE 147

  Fly   242 KLRKLHMIEYPNYKYRPQKKQTRSP-GSLKPNQDADGCEARNDTTNNNNSLTTLAINGTTTAGRK 305
            :||..||.|||:|||:|:||..::| |:|:........:.:....           .|.:...|:
 Worm   148 RLRVCHMQEYPDYKYKPRKKPKKNPDGTLQQPAQPQAPQQQQAPP-----------RGASPQARQ 201

  Fly   306 SKRSTSTCQSGS------ASKRLRND-SGDT----SSKPKYEVKMESAEQLNSADIILPSA--DN 357
            .||..:..||.:      .|.::..| .|:.    :.|..:.....|..:...|.:...|.  |:
 Worm   202 RKRPNTDQQSETQQFQNFKSVKVEQDWMGNAHMSHAQKMPFHPSYPSPSEFGHAPLTPESGFYDD 266

  Fly   358 LISYQ-----------SSEYLPLSTLSNADCDEKLHSEL-----------------SSGPLESRE 394
            ..:.|           :|...|| .::|...|..:..::                 :|.|...::
 Worm   267 YFTQQHHQQHFASQHHNSAGSPL-RMTNLGMDMGMPPQMMGHNSGFGAGNHPFYLHTSPPSVDQD 330

  Fly   395 NLSEVVNRFLPLFLGGNEDSQLGVSSLTQSQHNQSDP-TAGL------------MDNISDISPIN 446
            ::..:            .....|.:..:.|:.:.|.| :||:            :|::..|.|
 Worm   331 DMRSL------------SSGSSGYADCSASEQSTSSPNSAGVVTMATAATTTTHLDDLEQICP-- 381

  Fly   447 DREELTEEVMRYLPYLEVNPSSDGLTLKVESS 478
              ...|.|::.|       |.||.|.:.:..|
 Worm   382 --TVTTGELVNY-------PWSDALGIDINFS 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox14	NP_476894.1	HMG-box_SoxC	186..261	CDD:438838	52/74 (70%)
sem-2	NP_740846.1	HMG-box_SoxC	92..159	CDD:438838	47/66 (71%)