Protein Alignment Sox14 and sem-2

DIOPT Version :9

• Sequence 1: NP_001286801.1
• Gene: Sox14 / 37822
• FlyBaseID: FBgn0005612
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_740846.1
• Gene: sem-2 / 172162
• WormBaseID: WBGene00004771
• Length: 404
• Species: Caenorhabditis elegans
• Alignment Length: 487
• Identity: 125/487 - (25%)
• Similarity: 188/487 - (38%)
• Gaps: 157/487 - (32%)

  Fly    50 PHTLPPF---SPSPSPASSPSPAPAQTPGAQKTQSQAAITHPAAVASPSAPVAAAAPKTPKTPEP 111
            ||.:||.   :.:.:.|||.|.|...|.......||....||...|:..
 Worm    17 PHMMPPINWAAAAIAVASSTSGATNATSSNSVATSQQLQHHPYGTAAGG---------------- 65

  Fly   112 RSTHTHTHTHSQHFSPPPRESEMDGERSPSHSGHEMTLSMDGIDSSLVFGSARVPVNSSTPYSDA 176
                   :.|:|...|                                        .|.||||||
 Worm    66 -------YKHAQQAIP----------------------------------------KSVTPYSDA 83

  Fly   177 TRTKKHSPGHIKRPMNAFMVWSQMERRKICERTPDLHNAEISKELGRRWQLLSKDDKQPYIIEAE 241
            |..|| |..||||||||||||||||||||||..||:|||||||:||.||:.|:.::|.|::.|||
 Worm    84 TNCKK-SSNHIKRPMNAFMVWSQMERRKICEHQPDMHNAEISKQLGSRWRSLTDEEKAPFVAEAE 147

  Fly   242 KLRKLHMIEYPNYKYRPQKKQTRSP-GSLKPNQDADGCEARNDTTNNNNSLTTLAINGTTTAGRK 305
            :||..||.|||:|||:|:||..::| |:|:........:.:....           .|.:...|:
 Worm   148 RLRVCHMQEYPDYKYKPRKKPKKNPDGTLQQPAQPQAPQQQQAPP-----------RGASPQARQ 201

  Fly   306 SKRSTSTCQSGS------ASKRLRND-SGDT----SSKPKYEVKMESAEQLNSADIILPSA--DN 357
            .||..:..||.:      .|.::..| .|:.    :.|..:.....|..:...|.:...|.  |:
 Worm   202 RKRPNTDQQSETQQFQNFKSVKVEQDWMGNAHMSHAQKMPFHPSYPSPSEFGHAPLTPESGFYDD 266

  Fly   358 LISYQ-----------SSEYLPLSTLSNADCDEKLHSEL-----------------SSGPLESRE 394
            ..:.|           :|...|| .::|...|..:..::                 :|.|...::
 Worm   267 YFTQQHHQQHFASQHHNSAGSPL-RMTNLGMDMGMPPQMMGHNSGFGAGNHPFYLHTSPPSVDQD 330

  Fly   395 NLSEVVNRFLPLFLGGNEDSQLGVSSLTQSQHNQSDP-TAGL------------MDNISDISPIN 446
            ::..:            .....|.:..:.|:.:.|.| :||:            :|::..|.|
 Worm   331 DMRSL------------SSGSSGYADCSASEQSTSSPNSAGVVTMATAATTTTHLDDLEQICP-- 381

  Fly   447 DREELTEEVMRYLPYLEVNPSSDGLTLKVESS 478
              ...|.|::.|       |.||.|.:.:..|
 Worm   382 --TVTTGELVNY-------PWSDALGIDINFS 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox14	NP_001286801.1	SOX-TCF_HMG-box	186..257	CDD:238684	50/70 (71%)
sem-2	NP_740846.1	SOX-TCF_HMG-box	92..159	CDD:238684	47/66 (71%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	112	1.000	Domainoid score	I3898
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1275
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	1	1.000	-	-		oto18334
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R685
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.980