DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sox14 and Pdlim3

DIOPT Version :9

Sequence 1:	NP_001286801.1	Gene:	Sox14 / 37822	FlyBaseID:	FBgn0005612	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_446102.2	Gene:	Pdlim3 / 114108	RGDID:	620427	Length:	364	Species:	Rattus norvegicus

Alignment Length:	193	Identity:	43/193 - (22%)
Similarity:	60/193 - (31%)	Gaps:	55/193 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 SLRPGTVPTVPATTPAR------PATITIQRRHPAPKADSTPHTLPPFSPSPSPASSPS-PAPAQ 72
            ::||     .|...|.|      |:.|........|.:.||..|:.|.....:...:|: |...:
  Rat   120 NIRP-----KPFIIPGRTSGCSTPSGIDCGSGRSTPSSVSTVSTICPGDLKVAAKMAPNIPLEME 179

  Fly    73 TPGAQKTQSQAAITHPAAVASP-------SAPVAAAAPKTPKTPEPRSTHTHTHTHSQHFSPPPR 130
            .||.:...:|  ...|..:.|.       ...|:.|..:||...||.:            |.||:
  Rat   180 LPGVKIVHAQ--FNTPMQLYSDDNIMETLQGQVSTALGETPSMSEPTA------------SVPPQ 230

  Fly   131 -------ESEMDGERSPSHSGHEMTLS---MDGIDSSLV-FGSARVPVNSSTPYSDATRTKKH 182
                   ....|...:|..||....|.   .||.|.... ..|.|.||           ||.|
  Rat   231 SDVYRMLHDNRDEPAAPRQSGSFRVLQELVNDGSDDRPAGTRSVRAPV-----------TKVH 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sox14	NP_001286801.1	SOX-TCF_HMG-box	186..257	CDD:238684
Pdlim3	NP_446102.2	PDZ_signaling	2..80	CDD:238492
		DUF4749	184..263	CDD:406377	17/92 (18%)
		LIM_ALP	294..346	CDD:188834
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1703
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900