Protein Alignment Sox14 and HMG20B

DIOPT Version :10

• Sequence 1: NP_476894.1
• Gene: Sox14 / 37822
• FlyBaseID: FBgn0005612
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_006330.2
• Gene: HMG20B / 10362
• HGNCID: 5002
• Length: 317
• Species: Homo sapiens
• Alignment Length: 317
• Identity: 72/317 - (22%)
• Similarity: 110/317 - (34%)
• Gaps: 87/317 - (27%)

  Fly    94 PSAPVAAAAPKTPKTPEPRSTHTHTHTHSQH--FSPPPRESEMDGERSPSHSGHEMTLSMDGIDS 156
            |..|.|||||...|.|            .||  |....::...:|.|:.....||
Human     5 PKQPGAAAAPAGGKAP------------GQHGGFVVTVKQERGEGPRAGEKGSHE---------- 47

  Fly   157 SLVFGSARVPVNSSTPYSDATRTKKHSPGHIKRPMNAFMVWSQMERRKICERTPDLHNAEISKEL 221
                   ..|| ....:....:.||..|...|.|:..::.:....|.:|..|.|||...||:|.|
Human    48 -------EEPV-KKRGWPKGKKRKKILPNGPKAPVTGYVRFLNERREQIRTRHPDLPFPEITKML 104

  Fly   222 GRRWQLLSKDDKQPYIIEAEKLRKLHMIE---YPN---YKYRPQKKQTRSPGSLKPNQDADGCEA 280
            |..|..|...:||.|:.|||:.::.:|.|   |..   ||...:|.|.:   .:|....:.|
Human   105 GAEWSKLQPTEKQRYLDEAEREKQQYMKELRAYQQSEAYKMCTEKIQEK---KIKKEDSSSG--- 163

  Fly   281 RNDTTNNNNSLTTLAINGTTTAGRKSKRSTSTCQSGSASKRLRNDSGDTSSKPKYEVKMESAEQL 345
                      |....:||                         :..||......::|.:.:.|.|
Human   164 ----------LMNTLLNG-------------------------HKGGDCDGFSTFDVPIFTEEFL 193

  Fly   346 N-----SADIILPSADNLISYQSSEYLPLSTLSNADCDEKLHSELSSGPLESRENLS 397
            :     .|::......|:...:.:..|...|.|.:...|:|..||:   ||.|..|:
Human   194 DQNKAREAELRRLRKMNVAFEEQNAVLQRHTQSMSSARERLEQELA---LEERRTLA 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox14	NP_476894.1	HMG-box_SoxC	186..261	CDD:438838	26/80 (33%)
HMG20B	NP_006330.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..71		21/95 (22%)
		HMG-box_HMG20B	69..147	CDD:438834	26/77 (34%)