Protein Alignment Sox14 and sox17b.2

DIOPT Version :9

• Sequence 1: NP_001286801.1
• Gene: Sox14 / 37822
• FlyBaseID: FBgn0005612
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_001090837.1
• Gene: sox17b.2 / 100038235
• XenbaseID: XB-GENE-495335
• Length: 351
• Species: Xenopus tropicalis
• Alignment Length: 393
• Identity: 100/393 - (25%)
• Similarity: 172/393 - (43%)
• Gaps: 92/393 - (23%)

  Fly   171 TPYSDATRTKKH---------SPGHIKRPMNAFMVWSQMERRKICERTPDLHNAEISKELGRRWQ 226
            |.:.|| :|||.         :...|:|||||||||::.||:::.::.|||||||:||.||:.|:
 Frog    12 TMFQDA-KTKKEAGSANSRGKAEARIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWK 75

  Fly   227 LLSKDDKQPYIIEAEKLRKLHMIEYPNYKYRP-QKKQTRS------PGSLKPNQDADGCEARNDT 284
            .|:...|:|::.|||:||..|:.:||:||||| :|||.:.      |.:..|.....||   |..
 Frog    76 SLTLASKRPFVKEAERLRVQHIQDYPDYKYRPRRKKQVKREEEGFLPSADIPGPQVMGC---NAM 137

  Fly   285 TNNNNSLTTLAINGTTTAGRKSKRSTSTCQSGSASKRLRNDSG---DTSSKPKYEVKMESAEQLN 346
            ...|..:        ..:|:.|::|..| .:|....  .|..|   ...:.|||.:..      |
 Frog   138 VGQNYKM--------QYSGQNSQQSQIT-PAGYFED--HNPVGFYYRGYNVPKYYMSQ------N 185

  Fly   347 SADIILPSAD---NLISYQ-SSEYLPLSTLSNADCDEKLHSELSSGPLESRENLSEVVNRFLPLF 407
            |:....|...   ..:||. :|.|:|....::|....|        .:..:||:.:
 Frog   186 SSGYCSPPTQGEYQALSYNFNSSYIPYQQNASAPAMGK--------QMAVKENIIQ--------- 233

  Fly   408 LGGNEDSQLGV--SSLTQSQHN---------QSDPTAGLMDNISDISPINDREELTEEVMRYLPY 461
                |..:.|:  ..::...:|         ::.|.|    .....|.::..:::..:  .|||
 Frog   234 ----ESPEHGIMGCQVSPQMYNGQMYVPECAKTHPVA----QTEQHSSLHQSQQMVTQ--NYLP- 287

  Fly   462 LEVNPSSDG-LTLKVESSSLLGKPLNEPVFDSE--DNIVNDANLHSASHQIPPYVPDSHD-CFAE 522
                ...|| |...::.:......:.||..|:|  ..|..|:..:| ::.:|..:.:::. |:.:
 Frog   288 ----SQQDGHLESDIDKTEFDQYLMYEPKSDTELIYTIDQDSGAYS-TNLLPSLISEANSVCYYD 347

  Fly   523 DCG 525
            .||
 Frog   348 YCG 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox14	NP_001286801.1	SOX-TCF_HMG-box	186..257	CDD:238684	37/70 (53%)
sox17b.2	NP_001090837.1	SOX-TCF_HMG-box	35..106	CDD:238684	37/70 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000028
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10270
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R685
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.040