Protein Alignment Sox14 and sox17b.2

DIOPT Version :10

• Sequence 1: NP_476894.1
• Gene: Sox14 / 37822
• FlyBaseID: FBgn0005612
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_001090837.1
• Gene: sox17b.2 / 100038235
• XenbaseID: XB-GENE-495335
• Length: 351
• Species: Xenopus tropicalis
• Alignment Length: 393
• Identity: 100/393 - (25%)
• Similarity: 172/393 - (43%)
• Gaps: 92/393 - (23%)

  Fly   171 TPYSDATRTKKH---------SPGHIKRPMNAFMVWSQMERRKICERTPDLHNAEISKELGRRWQ 226
            |.:.|| :|||.         :...|:|||||||||::.||:::.::.|||||||:||.||:.|:
 Frog    12 TMFQDA-KTKKEAGSANSRGKAEARIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWK 75

  Fly   227 LLSKDDKQPYIIEAEKLRKLHMIEYPNYKYRP-QKKQTRS------PGSLKPNQDADGCEARNDT 284
            .|:...|:|::.|||:||..|:.:||:||||| :|||.:.      |.:..|.....||   |..
 Frog    76 SLTLASKRPFVKEAERLRVQHIQDYPDYKYRPRRKKQVKREEEGFLPSADIPGPQVMGC---NAM 137

  Fly   285 TNNNNSLTTLAINGTTTAGRKSKRSTSTCQSGSASKRLRNDSG---DTSSKPKYEVKMESAEQLN 346
            ...|..:        ..:|:.|::|..| .:|....  .|..|   ...:.|||.:..      |
 Frog   138 VGQNYKM--------QYSGQNSQQSQIT-PAGYFED--HNPVGFYYRGYNVPKYYMSQ------N 185

  Fly   347 SADIILPSAD---NLISYQ-SSEYLPLSTLSNADCDEKLHSELSSGPLESRENLSEVVNRFLPLF 407
            |:....|...   ..:||. :|.|:|....::|....|        .:..:||:.:
 Frog   186 SSGYCSPPTQGEYQALSYNFNSSYIPYQQNASAPAMGK--------QMAVKENIIQ--------- 233

  Fly   408 LGGNEDSQLGV--SSLTQSQHN---------QSDPTAGLMDNISDISPINDREELTEEVMRYLPY 461
                |..:.|:  ..::...:|         ::.|.|    .....|.::..:::..:  .|||
 Frog   234 ----ESPEHGIMGCQVSPQMYNGQMYVPECAKTHPVA----QTEQHSSLHQSQQMVTQ--NYLP- 287

  Fly   462 LEVNPSSDG-LTLKVESSSLLGKPLNEPVFDSE--DNIVNDANLHSASHQIPPYVPDSHD-CFAE 522
                ...|| |...::.:......:.||..|:|  ..|..|:..:| ::.:|..:.:::. |:.:
 Frog   288 ----SQQDGHLESDIDKTEFDQYLMYEPKSDTELIYTIDQDSGAYS-TNLLPSLISEANSVCYYD 347

  Fly   523 DCG 525
            .||
 Frog   348 YCG 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox14	NP_476894.1	HMG-box_SoxC	186..261	CDD:438838	40/75 (53%)
sox17b.2	NP_001090837.1	HMG-box_SoxF_SOX17	30..110	CDD:438850	40/79 (51%)