DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Alas and BIOF

DIOPT Version :9

Sequence 1:	NP_477281.1	Gene:	Alas / 37815	FlyBaseID:	FBgn0020764	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_974731.1	Gene:	BIOF / 830339	AraportID:	AT5G04620	Length:	476	Species:	Arabidopsis thaliana

Alignment Length:	395	Identity:	123/395 - (31%)
Similarity:	204/395 - (51%)	Gaps:	30/395 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 AGDGLFPHALEYSERTEKPITVWCSNDYLGMSAHPGVKRAVQDALNRHGSGAGGTRNISGNSLHH 186
            :||.|    .|..:...|.:.::..|||||:|:||.:..|..:|:..:|.|..|:..|.|.:.:|
plant    89 SGDAL----AECRKGRFKKLLLFSGNDYLGLSSHPTISNAAANAVKEYGMGPKGSALICGYTTYH 149

  Fly   187 ERLESKLAELHQKEAALLFTSCFVANDSTLF---TLAKLLPG---------CEIFSDAGNHASMI 239
            ..|||.||:|.:||..|:..:.|.||.:.:.   ::|.||..         ..|||||.||||:|
plant   150 RLLESSLAQLKKKEDCLVCPTGFAANMAAMVAIGSVASLLAASGKPLKNEKVAIFSDALNHASII 214

  Fly   240 MGI----RNSGVPKHIFRHNDVDHLHQLLKQTDKSVPKIVAFETVHSMTGAICPLEELLDVAHEH 300
            .|:    |...|...::||.|:.||:.||... |...|:|..:::.||.|...|:|||..:..::
plant   215 DGVRLAERQGNVEVFVYRHCDMYHLNSLLSNC-KMKRKVVVTDSLFSMDGDFAPMEELSQLRKKY 278

  Fly   301 GAITFIDEVHAVGLYGDHGAGVGERDGVLHKMDIISGTLGKAFGNIGGYIAGTHNLVDMIRSYAA 365
            |.:..||:.|...:.|::|.||.|.......:|:..|||.||.|..||:||.:.....:|:|...
plant   279 GFLLVIDDAHGTFVCGENGGGVAEEFNCEADVDLCVGTLSKAAGCHGGFIACSKKWKQLIQSRGR 343

  Fly   366 GFIFTTSLPPTVLCGALEAVNILASEEGRQLRHLHQRNVSYLKSLLKREGFPVEETPSHIIPIKI 430
            .|||:|::|..:...|..|| ::|.:|..:.:.:.:|    :|...:..|..:.   |.||.:.:
plant   344 SFIFSTAIPVPMAAAAYAAV-VVARKEIWRRKAIWER----VKEFKELSGVDIS---SPIISLVV 400

  Fly   431 GDPLKSSQISNVLIEQFGHYLQSINYPTVARGQEKLRLAPTPFHTFEMMNALVTDLKKVWEMVDL 495
            |:..|:.:.|..|::. |.::.:|..|||.....:||:..:..||.|.:..|:|.|....:..:.
plant   401 GNQEKALKASRYLLKS-GFHVMAIRPPTVPPNSCRLRVTLSAAHTTEDVKKLITALSSCLDFDNT 464

  Fly   496 STNVP 500
            :|::|
plant   465 ATHIP 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alas	NP_477281.1	AAT_I	93..495	CDD:302748	121/388 (31%)
Alas	NP_477281.1	BioF	95..490	CDD:223234	121/383 (32%)
BIOF	NP_974731.1	PLN02955	1..476	CDD:178541	123/395 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	175	1.000	Domainoid score	I1100
eggNOG	1	0.900	-	-		E1_COG0156
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58214
OrthoDB	1	1.010	-	-		D930001at2759
OrthoFinder	1	1.000	-	-		FOG0000902
OrthoInspector	1	1.000	-	-		otm2603
orthoMCL	1	0.900	-	-		OOG6_100359
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.730