Protein Alignment Alas and alas1

DIOPT Version :9

• Sequence 1: NP_477281.1
• Gene: Alas / 37815
• FlyBaseID: FBgn0020764
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_958444.1
• Gene: alas1 / 64608
• ZFINID: ZDB-GENE-001229-2
• Length: 613
• Species: Danio rerio
• Alignment Length: 591
• Identity: 290/591 - (49%)
• Similarity: 371/591 - (62%)
• Gaps: 92/591 - (15%)

  Fly     1 MQCPFLNRFTASFIRNYAETLCQSYGSHCPVV----GKTLVSGEKKLSLVAASVTRSHSTGANAH 61
            ::||||:|...:|::...::|. :|...|||:    .:.|:   :.|...:||..:...:.:..|
Zfish     5 IRCPFLSRVPQTFLQQARKSLV-AYAVKCPVMMDLASRPLL---RPLCSSSASFQKVEDSSSAGH 65

  Fly    62 ANAGGPAT-ANATAPVSAPASADPGKASAKE---------------------------------- 91
            ..:..||. |...||.:..|||......|.|
Zfish    66 EASDAPAVPAGHPAPPAGHASASKCPFLAAEMSQKNSGVVRQASMALQEDVSEVRTVQKDVSASA 130

  Fly    92 --------------------------------------TFPYERFFNEQIMKKKRDHSYRVFKKV 118
                                                  :|.|:.||.::|.:||.||:|||||.|
Zfish   131 LTPLKDGMNGGNLMKKLMKQRPAHVSHLLQDNMPKNVSSFRYDEFFEKKIEEKKSDHTYRVFKTV 195

  Fly   119 NRLAGDGLFPHALEYSERT--EKPITVWCSNDYLGMSAHPGVKRAVQDALNRHGSGAGGTRNISG 181
            ||.|.:  ||.|.:|:|..  ::.::|||||||||||.||.|.:.:.|.|.:|||||||||||||
Zfish   196 NRRATE--FPMADDYTESLSFKRNVSVWCSNDYLGMSRHPRVVQTIMDTLGKHGSGAGGTRNISG 258

  Fly   182 NSLHHERLESKLAELHQKEAALLFTSCFVANDSTLFTLAKLLPGCEIFSDAGNHASMIMGIRNSG 246
            .|..|..||.:||:||.|:|||||||||||||||||||||::|||||:||||||||||.||||||
Zfish   259 TSKFHVDLEHELADLHGKDAALLFTSCFVANDSTLFTLAKMMPGCEIYSDAGNHASMIQGIRNSG 323

  Fly   247 VPKHIFRHNDVDHLHQLLKQTDKSVPKIVAFETVHSMTGAICPLEELLDVAHEHGAITFIDEVHA 311
            ..|.||||||..||.:||:::|.|.||||||||||||.||:||||:|.|||||.||:||:|||||
Zfish   324 AKKFIFRHNDAKHLRELLEKSDPSTPKIVAFETVHSMDGAVCPLEQLCDVAHEFGAVTFVDEVHA 388

  Fly   312 VGLYGDHGAGVGERDGVLHKMDIISGTLGKAFGNIGGYIAGTHNLVDMIRSYAAGFIFTTSLPPT 376
            |||||..|.|:|:||.|:|||||||||||||||.:|||||.||.|||.:|||||||||||||||.
Zfish   389 VGLYGPRGGGIGDRDSVMHKMDIISGTLGKAFGCVGGYIASTHALVDTVRSYAAGFIFTTSLPPM 453

  Fly   377 VLCGALEAVNILASEEGRQLRHLHQRNVSYLKSLLKREGFPVEETPSHIIPIKIGDPLKSSQISN 441
            :|.||.::|.||.|||||.||..|||||:.|:.:|...|.||...||||||:::.|..|::::.:
Zfish   454 LLSGARQSVQILKSEEGRTLRRKHQRNVTLLRQMLMDSGLPVIHCPSHIIPVRVADAEKNTEVCD 518

  Fly   442 VLIEQFGHYLQSINYPTVARGQEKLRLAPTPFHTFEMMNALVTDLKKVWEMVDLSTNVPLSPNA- 505
            :::.::..|:|:|||||||||:|.||:||||.||.:||...|..|.:.|..|.|    ||.|::
Zfish   519 IMMSRYNIYVQAINYPTVARGEELLRIAPTPHHTPQMMKYFVDKLTQTWTEVGL----PLKPHSS 579

  Fly   506 --CMFC 509
              |.||
Zfish   580 AECNFC 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alas	NP_477281.1	AAT_I	93..495	CDD:302748	257/403 (64%)
		BioF	95..490	CDD:223234	254/396 (64%)
alas1	NP_958444.1	Preseq_ALAS	4..120	CDD:286162	26/118 (22%)
		AAT_I	170..575	CDD:302748	259/410 (63%)
		BioF	170..567	CDD:223234	255/398 (64%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	488	1.000	Domainoid score	I370
eggNOG	1	0.900	-	-		E1_COG0156
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	571	1.000	Inparanoid score	I1024
OMA	1	1.010	-	-		QHG58214
OrthoDB	1	1.010	-	-		D306770at33208
OrthoFinder	1	1.000	-	-		FOG0000902
OrthoInspector	1	1.000	-	-		otm25920
orthoMCL	1	0.900	-	-		OOG6_100359
Panther	1	1.100	-	-	LDO	PTHR13693
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R554
SonicParanoid	1	1.000	-	-		X1924
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.870