Protein Alignment Alas and alas1

DIOPT Version :10

• Sequence 1: NP_477281.1
• Gene: Alas / 37815
• FlyBaseID: FBgn0020764
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_958444.1
• Gene: alas1 / 64608
• ZFINID: ZDB-GENE-001229-2
• Length: 613
• Species: Danio rerio
• Alignment Length: 591
• Identity: 290/591 - (49%)
• Similarity: 371/591 - (62%)
• Gaps: 92/591 - (15%)

  Fly     1 MQCPFLNRFTASFIRNYAETLCQSYGSHCPVV----GKTLVSGEKKLSLVAASVTRSHSTGANAH 61
            ::||||:|...:|::...::|. :|...|||:    .:.|:   :.|...:||..:...:.:..|
Zfish     5 IRCPFLSRVPQTFLQQARKSLV-AYAVKCPVMMDLASRPLL---RPLCSSSASFQKVEDSSSAGH 65

  Fly    62 ANAGGPAT-ANATAPVSAPASADPGKASAKE---------------------------------- 91
            ..:..||. |...||.:..|||......|.|
Zfish    66 EASDAPAVPAGHPAPPAGHASASKCPFLAAEMSQKNSGVVRQASMALQEDVSEVRTVQKDVSASA 130

  Fly    92 --------------------------------------TFPYERFFNEQIMKKKRDHSYRVFKKV 118
                                                  :|.|:.||.::|.:||.||:|||||.|
Zfish   131 LTPLKDGMNGGNLMKKLMKQRPAHVSHLLQDNMPKNVSSFRYDEFFEKKIEEKKSDHTYRVFKTV 195

  Fly   119 NRLAGDGLFPHALEYSERT--EKPITVWCSNDYLGMSAHPGVKRAVQDALNRHGSGAGGTRNISG 181
            ||.|.:  ||.|.:|:|..  ::.::|||||||||||.||.|.:.:.|.|.:|||||||||||||
Zfish   196 NRRATE--FPMADDYTESLSFKRNVSVWCSNDYLGMSRHPRVVQTIMDTLGKHGSGAGGTRNISG 258

  Fly   182 NSLHHERLESKLAELHQKEAALLFTSCFVANDSTLFTLAKLLPGCEIFSDAGNHASMIMGIRNSG 246
            .|..|..||.:||:||.|:|||||||||||||||||||||::|||||:||||||||||.||||||
Zfish   259 TSKFHVDLEHELADLHGKDAALLFTSCFVANDSTLFTLAKMMPGCEIYSDAGNHASMIQGIRNSG 323

  Fly   247 VPKHIFRHNDVDHLHQLLKQTDKSVPKIVAFETVHSMTGAICPLEELLDVAHEHGAITFIDEVHA 311
            ..|.||||||..||.:||:::|.|.||||||||||||.||:||||:|.|||||.||:||:|||||
Zfish   324 AKKFIFRHNDAKHLRELLEKSDPSTPKIVAFETVHSMDGAVCPLEQLCDVAHEFGAVTFVDEVHA 388

  Fly   312 VGLYGDHGAGVGERDGVLHKMDIISGTLGKAFGNIGGYIAGTHNLVDMIRSYAAGFIFTTSLPPT 376
            |||||..|.|:|:||.|:|||||||||||||||.:|||||.||.|||.:|||||||||||||||.
Zfish   389 VGLYGPRGGGIGDRDSVMHKMDIISGTLGKAFGCVGGYIASTHALVDTVRSYAAGFIFTTSLPPM 453

  Fly   377 VLCGALEAVNILASEEGRQLRHLHQRNVSYLKSLLKREGFPVEETPSHIIPIKIGDPLKSSQISN 441
            :|.||.::|.||.|||||.||..|||||:.|:.:|...|.||...||||||:::.|..|::::.:
Zfish   454 LLSGARQSVQILKSEEGRTLRRKHQRNVTLLRQMLMDSGLPVIHCPSHIIPVRVADAEKNTEVCD 518

  Fly   442 VLIEQFGHYLQSINYPTVARGQEKLRLAPTPFHTFEMMNALVTDLKKVWEMVDLSTNVPLSPNA- 505
            :::.::..|:|:|||||||||:|.||:||||.||.:||...|..|.:.|..|.|    ||.|::
Zfish   519 IMMSRYNIYVQAINYPTVARGEELLRIAPTPHHTPQMMKYFVDKLTQTWTEVGL----PLKPHSS 579

  Fly   506 --CMFC 509
              |.||
Zfish   580 AECNFC 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alas	NP_477281.1	AAT_I	93..495	CDD:450240	257/403 (64%)
alas1	NP_958444.1	Preseq_ALAS	1..120	CDD:462658	26/118 (22%)
		AAT_I	170..575	CDD:450240	259/410 (63%)