Protein Alignment Alas and alas1

DIOPT Version :9

• Sequence 1: NP_477281.1
• Gene: Alas / 37815
• FlyBaseID: FBgn0020764
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_001008072.1
• Gene: alas1 / 493434
• XenbaseID: XB-GENE-975179
• Length: 628
• Species: Xenopus tropicalis
• Alignment Length: 606
• Identity: 288/606 - (47%)
• Similarity: 372/606 - (61%)
• Gaps: 110/606 - (18%)

  Fly     2 QCPFLNRFTASFIRNYAETLCQSYGSHCPVVGKTLVSGEKKLSLVAASVTRSHS----------- 55
            :||||:|.:.:|::...::|. :|..:|||     :.|.|.||..:.|.:..|.
 Frog     7 RCPFLSRVSQTFLQKAGKSLV-TYAQNCPV-----MMGTKPLSCASLSTSAVHQQETKETSDSKT 65

  Fly    56 -----------TGANAHANAGGPATANATA----------------------------------- 74
                       ||:...|:..|..:..:.:
 Frog    66 PLNRTQVQGGLTGSQVPADHPGAVSGQSASKCPFLAAQMVQENSSVIRKASPETQEDVQKMQTMR 130

  Fly    75 -PVSAPASADPGKA-----------------------------------SAKETFPYERFFNEQI 103
             .:..|.:...|:|                                   .|.:||.|::||.::|
 Frog   131 KDLRGPITKGAGEAKMTLQKNRSVLEKFQESVLHQRPAVVSHLLQDNMPKAVKTFKYDKFFEKKI 195

  Fly   104 MKKKRDHSYRVFKKVNRLAGDGLFPHALEYSER--TEKPITVWCSNDYLGMSAHPGVKRAVQDAL 166
            .:||.||:|||||.|||.|  .:||.|.:||:.  ::|.::|||||||||||.||.|..||.:.|
 Frog   196 DEKKNDHTYRVFKTVNRRA--EVFPMADDYSDTLISKKTVSVWCSNDYLGMSRHPKVVGAVMETL 258

  Fly   167 NRHGSGAGGTRNISGNSLHHERLESKLAELHQKEAALLFTSCFVANDSTLFTLAKLLPGCEIFSD 231
            .:||:||||||||||.|..|..||.:||:||.|:|||||:|||||||||||||||:||||||:||
 Frog   259 KQHGAGAGGTRNISGTSKFHVELEHELADLHGKDAALLFSSCFVANDSTLFTLAKMLPGCEIYSD 323

  Fly   232 AGNHASMIMGIRNSGVPKHIFRHNDVDHLHQLLKQTDKSVPKIVAFETVHSMTGAICPLEELLDV 296
            ||||||||.|||||..||::||||||.||.:|||.:|.|.||||||||||||.||:|||||:.||
 Frog   324 AGNHASMIQGIRNSRAPKYVFRHNDVGHLRELLKNSDPSTPKIVAFETVHSMDGAVCPLEEMCDV 388

  Fly   297 AHEHGAITFIDEVHAVGLYGDHGAGVGERDGVLHKMDIISGTLGKAFGNIGGYIAGTHNLVDMIR 361
            :||:|||||:||||||||||..|.|:|:||||:.||||||||||||||.:|||||.|..|:|.:|
 Frog   389 SHEYGAITFVDEVHAVGLYGARGGGIGDRDGVMTKMDIISGTLGKAFGCVGGYIASTSALIDTVR 453

  Fly   362 SYAAGFIFTTSLPPTVLCGALEAVNILASEEGRQLRHLHQRNVSYLKSLLKREGFPVEETPSHII 426
            ||||||||||||||.:|.||:.:|.:|.||||:.||..|||||..::.:|...|.||...|||||
 Frog   454 SYAAGFIFTTSLPPMLLSGAIASVRVLKSEEGQALRRQHQRNVKLMRQMLMDSGLPVVHCPSHII 518

  Fly   427 PIKIGDPLKSSQISNVLIEQFGHYLQSINYPTVARGQEKLRLAPTPFHTFEMMNALVTDLKKVWE 491
            ||::.|..|:::|.:.|:..:..|:|:|||||||||:|.||:||||.|..:||:..:..|...|:
 Frog   519 PIRVSDAAKNTEICDKLMRDYNIYVQAINYPTVARGEELLRIAPTPHHNPQMMSYFLDKLLTTWK 583

  Fly   492 MVDLSTNVPLSPN---ACMFC 509
            .|||.    |.|:   .|.||
 Frog   584 SVDLE----LKPHPTAECNFC 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alas	NP_477281.1	AAT_I	93..495	CDD:302748	255/403 (63%)
		BioF	95..490	CDD:223234	252/396 (64%)
alas1	NP_001008072.1	Preseq_ALAS	3..127	CDD:312538	21/125 (17%)
		AAT_I	185..590	CDD:327488	257/410 (63%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	491	1.000	Domainoid score	I376
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	569	1.000	Inparanoid score	I1052
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D306770at33208
OrthoFinder	1	1.000	-	-		FOG0000902
OrthoInspector	1	1.000	-	-		otm48434
Panther	1	1.100	-	-	LDO	PTHR13693
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R554
SonicParanoid	1	1.000	-	-		X1924
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.190