Protein Alignment Alas and GCAT

DIOPT Version :9

• Sequence 1: NP_477281.1
• Gene: Alas / 37815
• FlyBaseID: FBgn0020764
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: XP_016884163.1
• Gene: GCAT / 23464
• HGNCID: 4188
• Length: 521
• Species: Homo sapiens
• Alignment Length: 473
• Identity: 131/473 - (27%)
• Similarity: 218/473 - (46%)
• Gaps: 100/473 - (21%)

  Fly   100 NEQIMKKKRDHSYRVFKKVNRLAGDGLFP-----------HALEYSERTEKPITVWCSNDYLGMS 153
            :|:::..::....|| ..|:...|..:||           |.|.::    ..|..:|:|:|||:|
Human    46 SERVITSRQGPHIRV-DGVSGGPGTVIFPGLPLPHLSCCIHLLSFT----SGILNFCANNYLGLS 105

  Fly   154 AHPGVKRAVQDALNRHGSGAGGTRNISGNSLHHERLESKLAELHQKEAALLFTSCFVANDSTLFT 218
            :||.|.:|...||...|:|....|.|.|....|:.||:|:|..||:|.|:|:.||:.||.....:
Human   106 SHPEVIQAGLQALEEFGAGLSSVRFICGTQSIHKNLEAKIARFHQREDAILYPSCYDANAGLFES 170

  Fly   219 LAKLLPGCE-------------------------------------------------------- 227
            .|.:.||.|
Human   171 RALVQPGTETRGPQREAQNTLPLYPEERPGWQYSFLICWSPGQGRSPGWLNDGSTLTASLQALLT 235

  Fly   228 ----IFSDAGNHASMIMGIRNSGVPKHIFRHNDVDHLHQLLKQTDKSVPKIVAFETVHSMTGAIC 288
                :.||..||||:|.|||.....|:.:||.|:..|...|::..|...::||.:...||.|.|.
Human   236 PEDAVLSDELNHASIIDGIRLCKAHKYRYRHLDMADLEAKLQEAQKHRLRLVATDGAFSMDGDIA 300

  Fly   289 PLEELLDVAHEHGAITFIDEVHAVGLYGDHGAGVGERDGVLHKMDIISGTLGKAFGNI-GGYIAG 352
            ||:|:..:|..:||:.|:||.||.|..|..|.|..|..||:.::.||:.|||||.|.. |||..|
Human   301 PLQEICCLASRYGALVFMDECHATGFLGPTGRGTDELLGVMDQVTIINSTLGKALGGASGGYTTG 365

  Fly   353 THNLVDMIRSYAAGFIFTTSLPPTVLCGALEAVNILA-----------------SEEGRQLRHLH 400
            ...||.::|..|..::|:.||||.|:..|.:|:::|.                 |::||.
Human   366 PGPLVSLLRQRARPYLFSNSLPPAVVGCASKALDLLMGSNTIVQSMAAKTQRCDSQQGRL----- 425

  Fly   401 QRNVSYLKSLLKREGFPVEETPSHIIPIKIGDPLKSSQISNVLIEQFGHYLQSINYPTVARGQEK 465
            ....::.:|.::..||.:......|.|:.:||...:|::::.:::: |.::...:||.|.:|:.:
Human   426 GGGETWFRSKMEAAGFTISGASHPICPVMLGDARLASRMADDMLKR-GIFVIGFSYPVVPKGKAR 489

  Fly   466 LRLAPTPFHTFEMMNALV 483
            :|:..:..|:.|.::..|
Human   490 IRVQISAVHSEEDIDRCV 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alas	NP_477281.1	AAT_I	93..495	CDD:302748	131/473 (28%)
		BioF	95..490	CDD:223234	131/473 (28%)
GCAT	XP_016884163.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0156
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58214
OrthoDB	1	1.010	-	-		D930001at2759
OrthoFinder	1	1.000	-	-		FOG0000902
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100359
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R554
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.760