Protein Alignment Alas and Sptlc2

DIOPT Version :10

• Sequence 1: NP_477281.1
• Gene: Alas / 37815
• FlyBaseID: FBgn0020764
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_035609.1
• Gene: Sptlc2 / 20773
• MGIID: 108074
• Length: 560
• Species: Mus musculus
• Alignment Length: 444
• Identity: 122/444 - (27%)
• Similarity: 211/444 - (47%)
• Gaps: 51/444 - (11%)

  Fly    95 YERFFNEQIMKKKRDHSYRVFKKV--------NRLAGDGLFPHALEYSERTEKPITVWCSNDYLG 151
            :|.|:...:..:.||:..|....|        .|.:.|  :..:.:|:....|.:....|.:|||
Mouse   116 FENFYTRNLYMRIRDNWNRPICSVPGAKVDIMERKSHD--YNWSFKYTGNIIKGVINMGSYNYLG 178

  Fly   152 MSAHPG-VKRAVQDALNRHGSGAGGTRNISGNSLHHERLESKLAELHQKEAALLFTSCFVANDST 215
            .:.:.| .:.|..:.|..:|:|...||...||...||.||..:|.....|||:.:...|..|...
Mouse   179 FARNTGSCQEAAAEVLKEYGAGVCSTRQEIGNLDKHEELEKLVARFLGVEAAMTYGMGFATNSMN 243

  Fly   216 LFTLAKLLPGCEIFSDAGNHASMIMGIRNSGVPKHIFRHNDVDHLHQLLK--------QTDKSVP 272
            :..|..  .||.|.||..||||:::|.|.||....||:||::..|.:|||        :|.:...
Mouse   244 IPALVG--KGCLILSDELNHASLVLGARLSGATIRIFKHNNMQSLEKLLKDAIVYGQPRTRRPWK 306

  Fly   273 KI-VAFETVHSMTGAICPLEELLDVAHEHGAITFIDEVHAVGLYGDHGAGVGERDGV-LHKMDII 335
            || :..|.::||.|:|..|.|::.:..::.|..::||.|::|..|..|.||.:..|: ...:|::
Mouse   307 KILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGALGPSGRGVVDYFGLDPEDVDVM 371

  Fly   336 SGTLGKAFGNIGGYIAGTHNLVDMIRSYAAGFIFTTSLPPTVLCGALEAVNILASEEGRQL--RH 398
            .||..|:||..||||.|...|:|.:|:::...::.||:.|.|:...:.::..:..::|..|  ..
Mouse   372 MGTFTKSFGASGGYIGGKKELIDYLRTHSHSAVYATSMSPPVMEQIITSMKCIMGQDGTSLGKEC 436

  Fly   399 LHQ--RNVSYLKSLLKREGFPV---EETPSHIIPIKIGDPLKSSQISNVLIEQFGHYLQSINYPT 458
            :.|  .|..|.:..||..||.:   |::|  ::|:.:..|.|        |..||..:...|...
Mouse   437 IQQLAENTRYFRRRLKEMGFIIYGNEDSP--VVPLMLYMPAK--------IGAFGREMLKRNIGV 491

  Fly   459 VARG-------QEKLRLAPTPFHTFEMMNALVTDLKKVWEMVDLSTN----VPL 501
            |..|       :.:.|...:..||.|:::..:.::.:|.:::.|..:    |||
Mouse   492 VVVGFPATPIIESRARFCLSAAHTKEILDTALKEIDEVGDLLQLKYSRHRLVPL 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alas	NP_477281.1	AAT_I	93..495	CDD:450240	118/432 (27%)
Sptlc2	NP_035609.1	AAT_I	65..540	CDD:450240	119/437 (27%)