DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fmo-1 and Fmo3

DIOPT Version :10

Sequence 1:NP_611859.1 Gene:Fmo-1 / 37814 FlyBaseID:FBgn0034943 Length:416 Species:Drosophila melanogaster
Sequence 2:NP_445885.2 Gene:Fmo3 / 84493 RGDID:619761 Length:531 Species:Rattus norvegicus


Alignment Length:462 Identity:133/462 - (28%)
Similarity:202/462 - (43%) Gaps:107/462 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 VCIIGAGTAGLCCARHSIANGFETTVFELSDRIGGTWVYNEATGAVNGIDVHSSMYKNLRTNLPK 68
            |.:||||.:||...|..:..|.|.|.||.||.:||.|.:::.|.     :..:|:|:::.||..|
  Rat     5 VAVIGAGVSGLAAIRSCLEEGLEPTCFERSDDVGGLWKFSDHTE-----EGRASIYQSVFTNSSK 64

  Fly    69 EVMGFPDFEIGANEASYVRSDEICDFLNQYANHFDLKKHIKFDSYVIRV-----LQRKTKWQVLF 128
            |:|.||||....:..:::.:.::.:::..:|...:|.|:|:|::.|.|:     .....||:|..
  Rat    65 EMMCFPDFPYPDDFPNFMHNSKLQEYITSFATEKNLLKYIQFETLVTRINKCPDFSTTGKWEVTT 129

  Fly   129 KDLVTNKIEFQYFDKVLVANGHY---HTPNYSQIPNMERFKGQFLHSHDFRSREVFEGKSVLVIG 190
            :.  .:|.|...||.|::.:||:   |.|..| .|.:.||||:..||.|::....::||.|||||
  Rat   130 EK--NSKKETAVFDAVMICSGHHVYPHLPKDS-FPGLNRFKGKCFHSRDYKEPGTWKGKRVLVIG 191

  Fly   191 AGPSGMDLSNIISRTADRVTISH-----------------------------------------H 214
            .|.||.|::..:|..|.:|.||.                                         :
  Rat   192 LGNSGCDIAAELSHVAQQVIISSRSGSWVMSRVWNDGYPWDMVVITRFQTFLKNNLPTAISDWWY 256

  Fly   215 LTDIGQHSFFEN----------------------------VQQKPDVRELDEKGAFFVDGS-YQE 250
            :..:......||                            |..||:|:|..|..|.|.||: ::.
  Rat   257 MKQMNARFKHENYGLMPLNGTLRKEPVFNDELPARILCGTVSIKPNVKEFTETSAVFEDGTVFEG 321

  Fly   251 FDTVFFCTGYKYAFPFLTVDSGIYVEDNYVQELYKQCI--NIRNPSMALIGLPFYVCAA-QMMDI 312
            .|.|.|.|||.||:|||  |..|....|....|||...  .:..|:||:|||...:.|| ...|:
  Rat   322 IDCVIFATGYGYAYPFL--DDSIIKSRNNEVTLYKGIFPPQLEKPTMAVIGLVQSLGAAIPTTDL 384

  Fly   313 QARFIMSYYNGSNELPSTEDMLKDTRDRMGK--LWAEGLRKRHAHMLGPK---QIDYFTDLSQTA 372
            |||:......|:..|||..||:.|..::|||  .|           .|..   |.||...:.:.|
  Rat   385 QARWAAQVIRGTCILPSVNDMMDDIDEKMGKKLKW-----------FGNSTTIQTDYIVYMDELA 438

  Fly   373 GVKNIKP 379
            .....||
  Rat   439 SFIGAKP 445

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fmo-1NP_611859.1 PLN02172 4..373 CDD:215116 130/454 (29%)
Fmo3NP_445885.2 FMO-like 2..530 CDD:395602 133/462 (29%)

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