DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fmo-1 and NOGC1

DIOPT Version :9

Sequence 1:	NP_611859.1	Gene:	Fmo-1 / 37814	FlyBaseID:	FBgn0034943	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_176446.1	Gene:	NOGC1 / 842555	AraportID:	AT1G62580	Length:	497	Species:	Arabidopsis thaliana

Alignment Length:	487	Identity:	139/487 - (28%)
Similarity:	216/487 - (44%)	Gaps:	95/487 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VCIIGAGTAGLCCARHSIANGFETTVFELSDRIGGTWVYN----------EATGAVNGIDVHSSM 58
            |.:||||.|||..||.....|....|||..:.|||.|.|.          :.|..|    :|||:
plant    14 VAVIGAGAAGLVAARELRREGHSVVVFERGNHIGGVWAYTPNVEPDPLSIDPTRPV----IHSSL 74

  Fly    59 YKNLRTNLPKEVMGFPDF------EIGANE-ASYVRSDEICDFLNQYANHFDLKKHIKFDSYVIR 116
            |.:|||.:|:|.|||.||      |.|:.: ..:....|:..:|..:...|.:::.|:|::.|:|
plant    75 YSSLRTIIPQECMGFTDFPFSTRLENGSRDPRRHPGHSEVLAYLRDFVREFKIEEMIRFETEVVR 139

  Fly   117 VLQ---RKTKWQVLFKDLVTNKIEFQYFDKVLVANGHYHTPNYSQIP------------NMERFK 166
            |.|   ...||:|..::.  ..|..:.:|.|:|.||||..|.::.||            .::.:.
plant   140 VEQAGENPKKWRVKSRNF--GDISDEIYDAVVVCNGHYTEPRHALIPGNKINHSFSIGLGIDTWP 202

  Fly   167 GQFLHSHDFRSREVFEGKSVLVIGAGPSGMDLSNIISRTADRVTISHHLT------------DIG 219
            |:.:|||::|..|..:.:.|:|||:..||:|:|..|:.....|.||...|            ::.
plant   203 GKQIHSHNYRVPEQVKDQVVVVIGSSVSGVDISRDIANVTKEVHISSRSTKPETYEKLPGYDNLW 267

  Fly   220 QHSFFENVQQKPDVRELDEKGAFFVDGSYQEFDTVFFCTGYKYAFPFLTVDSGIYVEDNYVQELY 284
            .||..|.|::...|        .|.:|.....||:..||||||.||||.....:.||||.|..||
plant   268 LHSNIETVREDGSV--------VFKNGKTVYADTIMHCTGYKYYFPFLDTKGEVTVEDNRVGPLY 324

  Fly   285 KQCI-NIRNPSMALIGLPFYVCAAQMMDI---------------------QARFIMSYYNGSNEL 327
            |... ...:|.::.||||:.....|.:|:                     |::::.:...|...|
plant   325 KHVFPPALSPGLSFIGLPWQNMKLQTLDVNELIGQCFGYLLVIPFPMFELQSKWVAAVLAGRVSL 389

  Fly   328 PSTEDMLKDTRDRMGKLWAEGLRKRHAHMLG--PKQIDYFTDLSQTAGVKNIKPVMTKLHNESSK 390
            ||.|:| :||:....||.|..:.||:.|::.  ..|..|...|:.......|:....::..:..|
plant   390 PSQEEM-EDTKMFYLKLEASCIPKRYTHLMAELDSQFVYNNWLADQCDYPRIEKWREQMFYKVFK 453

  Fly   391 CFNENLLHFREDNFAILDD--------ETFIK 414
            ........:::|    .||        |.|:|
plant   454 RIQSQASTYKDD----WDDDHLIAEAYEDFVK 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fmo-1	NP_611859.1	NADB_Rossmann	5..197	CDD:304358	71/223 (32%)
Fmo-1	NP_611859.1	NADB_Rossmann	185..>211	CDD:304358	10/25 (40%)
NOGC1	NP_176446.1	PLN02172	1..492	CDD:215116	139/487 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	150	1.000	Domainoid score	I1415
eggNOG	1	0.900	-	-		E1_COG2072
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H101446
Inparanoid	1	1.050	225	1.000	Inparanoid score	I1172
OMA	1	1.010	-	-		QHG55225
OrthoDB	1	1.010	-	-		D405736at2759
OrthoFinder	1	1.000	-	-		FOG0000093
OrthoInspector	1	1.000	-	-		mtm1034
orthoMCL	1	0.900	-	-		OOG6_100150
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X69
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.740