DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fmo-1 and FMO GS-OX2

DIOPT Version :9

Sequence 1:	NP_611859.1	Gene:	Fmo-1 / 37814	FlyBaseID:	FBgn0034943	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_001320894.1	Gene:	FMO GS-OX2 / 842551	AraportID:	AT1G62540	Length:	482	Species:	Arabidopsis thaliana

Alignment Length:	435	Identity:	130/435 - (29%)
Similarity:	213/435 - (48%)	Gaps:	63/435 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VCIIGAGTAGLCCARHSIANGFETTVFELSDRIGGTWVYN-EATGAVNGID-----VHSSMYKNL 62
            |.:||||.|||..||.....|....|.|....:||.|:|: :|......:|     ||||:|::|
plant    13 VVVIGAGAAGLVAARELSREGHTVVVLEREKEVGGLWIYSPKAESDPLSLDPTRSIVHSSVYESL 77

  Fly    63 RTNLPKEVMGFPDF-------EIGANEASYVRSDEICDFLNQYANHFDLKKHIKFDSYVIRVLQR 120
            |||||:|.|||.||       :...:...|....|:..:|..:|..|:|::.::|:..|:||...
plant    78 RTNLPRECMGFTDFPFVPRFDDESRDSRRYPSHMEVLAYLQDFAREFNLEEMVRFEIEVVRVEPV 142

  Fly   121 KTKWQVLFKDLVTNKIEF-QYFDKVLVANGHYHTPNYSQIPNMERFKGQFLHSHDFRSREVFEGK 184
            ..||:|..|  .:..:.. :.||.|:|.:|||..||.:.||.::.:.|:.:|||::|....||.:
plant   143 NGKWRVWSK--TSGGVSHDEIFDAVVVCSGHYTEPNVAHIPGIKSWPGKQIHSHNYRVPGPFENE 205

  Fly   185 SVLVIGAGPSGMDLSNIISRTADRVTISHHLTDIGQHSFFENVQQKPDVR-------ELD---EK 239
            .|:|||...||.|:|..|::.|..|.|:...::      |:..::.|..|       |:|   |.
plant   206 VVVVIGNFASGADISRDIAKVAKEVHIASRASE------FDTYEKLPVPRNNLWIHSEIDTAYED 264

  Fly   240 GAF-FVDGSYQEFDTVFFCTGYKYAFPFLTVDSGIYVEDNYVQELYKQCI-NIRNPSMALIGLPF 302
            |:. |.:|.....|::.:||||||.|.||..:..:.:::|.|:.|||... ...:|.::.:|||.
plant   265 GSIVFKNGKVVYADSIVYCTGYKYRFTFLETNGYMNIDENRVEHLYKHVFPPALSPGLSFVGLPS 329

  Fly   303 YVCAAQ-------------------------MMDIQARFIMSYYNGSNELPSTEDMLKDTRDRMG 342
            .|...|                         |.:||::::.:..:....||:.:.|::|......
plant   330 MVSLKQYLGVPSSSLTWFLSLSFFYQGIQFVMFEIQSKWVAAVLSRRVTLPTEDKMMEDISAWYA 394

  Fly   343 KLWAEGLRKRHAHMLGPKQIDYFTDLSQTAGVKNIKPVMTKLHNE 387
            .|.|.|:.||:.|.||..|.:|...:::..|.    |::....|:
plant   395 SLDAVGIPKRYTHKLGKIQSEYLNWVAEECGC----PLVEHWRNQ 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fmo-1	NP_611859.1	NADB_Rossmann	5..197	CDD:304358	73/205 (36%)
Fmo-1	NP_611859.1	NADB_Rossmann	185..>211	CDD:304358	11/25 (44%)
FMO GS-OX2	NP_001320894.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	150	1.000	Domainoid score	I1415
eggNOG	1	0.900	-	-		E1_COG2072
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H101446
Inparanoid	1	1.050	225	1.000	Inparanoid score	I1172
OMA	1	1.010	-	-		QHG55225
OrthoDB	1	1.010	-	-		D405736at2759
OrthoFinder	1	1.000	-	-		FOG0000093
OrthoInspector	1	1.000	-	-		mtm1034
orthoMCL	1	0.900	-	-		OOG6_100150
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X69
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.740