DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fmo-1 and FMO1

DIOPT Version :9

Sequence 1:	NP_611859.1	Gene:	Fmo-1 / 37814	FlyBaseID:	FBgn0034943	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_173359.3	Gene:	FMO1 / 838508	AraportID:	AT1G19250	Length:	530	Species:	Arabidopsis thaliana

Alignment Length:	519	Identity:	120/519 - (23%)
Similarity:	173/519 - (33%)	Gaps:	182/519 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VCIIGAGTAGLCCARHSIANGFETTVFELSDRIGGTWVYNEATGAVNGIDVHSSMYKNLRTNLPK 68
            |.|||||.:||..|::.:.:  ..||||.||.:||.|              .|..|:..:....:
plant    13 VAIIGAGVSGLAAAKNLVHH--NPTVFEASDSVGGVW--------------RSCTYETTKLQSAR 61

  Fly    69 EVMGFPDFEIGANEASYVRSD-------EICDFLNQYANHFDLKKHIKFDSYVIRV--------- 117
            ....|.||....|     |.|       ||.|:|..||.||||.|.:||.|.||.|
plant    62 VDYEFSDFPWPNN-----RDDTTFPPYLEILDYLESYAKHFDLLKFMKFGSKVIEVRFIGDGETP 121

  Fly   118 -----------LQRKTKWQVLFKDLVTNKIEFQYFDKVLVANGHY----HTPNYSQIPNMERFKG 167
                       |..|..|:|..:...:..|::..|:.|:|..|.|    ..|.:......|.|:|
plant   122 QMVDLGAYGNLLPGKPVWEVAVQIGDSGDIQWHAFEFVVVCTGKYGDVPRIPAFPAKKGPEMFQG 186

  Fly   168 QFLHSHDFRSRE------VFEGKSVLVIGAGPSGMDLS---------------NIISRT------ 205
            :.:||.|:...|      :..||.|.|||...|.:||:               .::.||
plant   187 KVMHSMDYCKLEKEEASTLLSGKKVAVIGFKKSAIDLALESALANQGEGGKACTMVVRTTHWGIP 251

  Fly   206 -------------ADRVTISHHLTDIGQHSF-----------------------------FENVQ 228
                         :.|.  |..|.|....||                             .|...
plant   252 HYWVWGLPFFLFYSSRA--SQFLHDRPNQSFLRTLFCLLFSLLRAVVSKFIESYVLWKLPLEKYG 314

  Fly   229 QKPD-------------------VRELD---------------EKGAFFVDGSYQEFDTVFFCTG 259
            .||:                   ..|.|               |:|..|.||:..|.|.|...||
plant   315 LKPNHSFEEDYASCQMAIIPENFFEEADKGMIRFKKSSKWWFYEEGIVFEDGTTLEADVVILATG 379

  Fly   260 Y------KYAFP-----FLTVDSGIYVEDNYVQELYKQCINIRNPSMALIGLPFYVCAAQMM--- 310
            |      |...|     :|...||       |..||:..|:...|:|..:|   ||.::..:
plant   380 YDGKKKLKAIVPEPFRTWLEFPSG-------VMPLYRGTIHPLIPNMGFVG---YVQSSSNLHTS 434

  Fly   311 DIQARFIMSYYNGSNELPSTEDMLKDTRDRMGKLWAEGLRKRHAHMLGPKQIDYFTDLSQTAGV 374
            ::::.::....:....|||.|.||......| ::.....|....|.:....|.:..|:....|:
plant   435 ELRSMWLSRLVDEKFRLPSKEKMLDQFLKEM-EVTRNSSRFYKRHCISTFSIQHADDMCNDMGL 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fmo-1	NP_611859.1	NADB_Rossmann	5..197	CDD:304358	67/228 (29%)
Fmo-1	NP_611859.1	NADB_Rossmann	185..>211	CDD:304358	10/59 (17%)
FMO1	NP_173359.3	FMO-like	12..520	CDD:109787	120/519 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2072
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D405736at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100150
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X69
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.720