DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fmo-1 and AT1G12160

DIOPT Version :9

Sequence 1:	NP_611859.1	Gene:	Fmo-1 / 37814	FlyBaseID:	FBgn0034943	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_172680.1	Gene:	AT1G12160 / 837768	AraportID:	AT1G12160	Length:	468	Species:	Arabidopsis thaliana

Alignment Length:	451	Identity:	141/451 - (31%)
Similarity:	224/451 - (49%)	Gaps:	41/451 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VCIIGAGTAGLCCARHSIANGFETTVFELSDRIGGTWVYNEATGAVN-GID-----VHSSMYKNL 62
            |.:||.|.|||...|.....|.....||....:||.|||.:...:.: .:|     ||||:|::|
plant    12 VAVIGLGAAGLVAVRELRREGHTVIGFEREKHVGGLWVYTDRVDSDSVSVDPDRTIVHSSIYQSL 76

  Fly    63 RTNLPKEVMGFPDFEIGANEAS-----YVRSDEICDFLNQYANHFDLKKHIKFDSYVIRV---LQ 119
            |||||:|.||:.||......:.     |....|:..:|..:|..|.::..|:|::.|:.|   .:
plant    77 RTNLPRECMGYSDFPFVTRSSDGDPRRYPDHREVLMYLQDFAKEFKIEDMIRFETEVLCVEPSPE 141

  Fly   120 RKTKWQVLFKDLVTNKIE-FQYFDKVLVANGHYHTPNYSQIPNMERFKGQFLHSHDFRSREVFEG 183
            ...||:|.||.  :|.:. .:.||.|:|.|||:..|..:.||.:|.:.|:.:|||::|..:.|:.
plant   142 NNRKWRVQFKS--SNGVSGEEIFDAVVVCNGHFTEPRLAHIPGIESWPGKQIHSHNYRIPDPFKD 204

  Fly   184 KSVLVIGAGPSGMDLSNIISRTADRVTISHHLTDIGQHSFFENVQQKPDVRELDEKGA-FFVDGS 247
            :.|:|||:..||.|:|..|:..|..|.||..:.....:..::|::..|.:....|.|: .|.:|.
plant   205 EVVIVIGSQASGNDISTDIATIAKEVHISSKMVASDSYGCYDNLRIHPTIYRAREDGSVVFRNGK 269

  Fly   248 YQEFDTVFFCTGYKYAFPFLTVDSGIYVEDNYVQELYKQCI-NIRNPSMALIGLPFYVCAAQMMD 311
            ....|.:..||||||.||||.....:.||||.|..|||... ....|.::.|||||......|.:
plant   270 VVFADAIVHCTGYKYHFPFLKTSGYVTVEDNRVGPLYKHVFPPALAPGISFIGLPFMGLQFFMFE 334

  Fly   312 IQARFIMSYYNGSNELPSTEDMLKDTRDRMGKLWAEGLRKRHAH---------MLGP-------- 359
            ||::::.|..:|..:||:.:.|:::......||...|:.||:.|         |||.
plant   335 IQSKWVASVLSGRVKLPAEDKMMEEAVAFYSKLEDLGIPKRYTHFLTDPRGNPMLGTFKPEDAVV 399

  Fly   360 -KQIDYFTDLSQTAGVKNIKPVMTKLHNESSK--CFNENLLHFREDNFAILDD--ETFIKL 415
             .|.|||..:::..|..:|:....:|:|.:.|  .|..:....|.|:..::::  ..|.||
plant   400 ISQSDYFNWIAKQCGCTSIERWRERLYNVAIKKVFFGGDSYRDRWDDDQLIEEVYREFAKL 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fmo-1	NP_611859.1	NADB_Rossmann	5..197	CDD:304358	70/206 (34%)
Fmo-1	NP_611859.1	NADB_Rossmann	185..>211	CDD:304358	11/25 (44%)
AT1G12160	NP_172680.1	PLN02172	9..461	CDD:215116	141/451 (31%)
		NAD_binding_8	14..>55	CDD:290186	15/40 (38%)
		P-loop_NTPase	171..>250	CDD:304359	25/78 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	150	1.000	Domainoid score	I1415
eggNOG	1	0.900	-	-		E1_COG2072
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H101446
Inparanoid	1	1.050	225	1.000	Inparanoid score	I1172
OMA	1	1.010	-	-		QHG55225
OrthoDB	1	1.010	-	-		D405736at2759
OrthoFinder	1	1.000	-	-		FOG0000093
OrthoInspector	1	1.000	-	-		mtm1034
orthoMCL	1	0.900	-	-		OOG6_100150
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X69
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.740