DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fmo-1 and FMO GS-OX5

DIOPT Version :9

Sequence 1:	NP_611859.1	Gene:	Fmo-1 / 37814	FlyBaseID:	FBgn0034943	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_001323223.1	Gene:	FMO GS-OX5 / 837766	AraportID:	AT1G12140	Length:	459	Species:	Arabidopsis thaliana

Alignment Length:	401	Identity:	130/401 - (32%)
Similarity:	199/401 - (49%)	Gaps:	40/401 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 MSVCIIGAGTAGLCCARHSIANGFETTVFELSDRIGGTWVY--NEATGAV----NGIDVHSSMYK 60
            ::|.:||||.|||..||..........|||...::||.|||  |.....:    |...||||:|.
plant    11 LNVAVIGAGAAGLVAARELRRENHTVVVFERDSKVGGLWVYTPNSEPDPLSLDPNRTIVHSSVYD 75

  Fly    61 NLRTNLPKEVMGFPDF--------EIGANEASYVRSDEICDFLNQYANHFDLKKHIKFDSYVIRV 117
            :||||||:|.||:.||        :...:...|....|:..:|..:|..|.|.:.::|.:.|:.|
plant    76 SLRTNLPRECMGYRDFPFVPRPEDDESRDSRRYPSHREVLAYLEDFAREFKLVEMVRFKTEVVLV 140

  Fly   118 LQRKTKWQVLFK--DLVTNKIEFQYFDKVLVANGHYHTPNYSQIPNMERFKGQFLHSHDFRSREV 180
            .....||:|..|  |.::..   :.||.|:|.||||..|..:.:|.::.:.|:.:|||::|..:.
plant   141 EPEDKKWRVQSKNSDGISKD---EIFDAVVVCNGHYTEPRVAHVPGIDSWPGKQIHSHNYRVPDQ 202

  Fly   181 FEGKSVLVIGAGPSGMDLSNIISRTADRVTISHH------------LTDIGQHSFFENVQQKPDV 233
            |:.:.|:|||...||.|:|..|:..|..|.|:..            ..::..||..|:|.:...:
plant   203 FKDQVVVVIGNFASGADISRDITGVAKEVHIASRSNPSKTYSKLPGSNNLWLHSMIESVHEDGTI 267

  Fly   234 RELDEKGAFFVDGSYQEFDTVFFCTGYKYAFPFLTVDSGIYVEDNYVQELYKQCI-NIRNPSMAL 297
                    .|.:|...:.||:..||||||.||||..:..|.||||.|..||:... ....|.::.
plant   268 --------VFQNGKVVQADTIVHCTGYKYHFPFLNTNGYITVEDNCVGPLYEHVFPPALAPGLSF 324

  Fly   298 IGLPFYVCAAQMMDIQARFIMSYYNGSNELPSTEDMLKDTRDRMGKLWAEGLRKRHAHMLGPKQI 362
            ||||:......|.::|::::.:..:|...|||.|.|::|......|..|.|..||:.|.||..|:
plant   325 IGLPWMTLQFFMFELQSKWVAAALSGRVTLPSEEKMMEDVTAYYAKREAFGQPKRYTHRLGGGQV 389

  Fly   363 DYFTDLSQTAG 373
            ||...:::..|
plant   390 DYLNWIAEQIG 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fmo-1	NP_611859.1	NADB_Rossmann	5..197	CDD:304358	71/207 (34%)
Fmo-1	NP_611859.1	NADB_Rossmann	185..>211	CDD:304358	11/25 (44%)
FMO GS-OX5	NP_001323223.1	PLN02172	1..459	CDD:215116	130/401 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	150	1.000	Domainoid score	I1415
eggNOG	1	0.900	-	-		E1_COG2072
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H101446
Inparanoid	1	1.050	225	1.000	Inparanoid score	I1172
OMA	1	1.010	-	-		QHG55225
OrthoDB	1	1.010	-	-		D405736at2759
OrthoFinder	1	1.000	-	-		FOG0000093
OrthoInspector	1	1.000	-	-		mtm1034
orthoMCL	1	0.900	-	-		OOG6_100150
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X69
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.740