DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fmo-1 and AT1G12130

DIOPT Version :9

Sequence 1:	NP_611859.1	Gene:	Fmo-1 / 37814	FlyBaseID:	FBgn0034943	Length:	416	Species:	Drosophila melanogaster
Sequence 2:	NP_172677.1	Gene:	AT1G12130 / 837765	AraportID:	AT1G12130	Length:	470	Species:	Arabidopsis thaliana

Alignment Length:	444	Identity:	147/444 - (33%)
Similarity:	221/444 - (49%)	Gaps:	48/444 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SVCIIGAGTAGLCCARHSIANGFETTVFELSDRIGGTWVYNEATGAVN----GID-----VHSSM 58
            :|.:||||.|||..||.....|...|:||...::||.||   .|..|.    .||     ||||:
plant    12 NVAVIGAGAAGLVAARELRREGHTVTIFERQKQVGGLWV---CTPNVEPDLLSIDPDRTVVHSSV 73

  Fly    59 YKNLRTNLPKEVMGFPDF-------EIGANEASYVRSDEICDFLNQYANHFDLKKHIKFDSYVIR 116
            |::||||||:|.||:.||       :...:...|....|:..:|..:|..|.:::.|:|::.|.|
plant    74 YQSLRTNLPRECMGYSDFPFVTRPDDESRDPRRYPDHREVMRYLQDFAKEFKIEEMIRFETEVFR 138

  Fly   117 V---LQRKTKWQVLFKDL--VTNKIEFQYFDKVLVANGHYHTPNYSQIPNMERFKGQFLHSHDFR 176
            |   .:...||:|.|:..  |:.:   ..||.|::.|||:..|..:.||.:|.:.|:.:|||::|
plant   139 VEPTAENSCKWRVQFRSSSGVSGE---DIFDAVVICNGHFTEPRLAHIPGIESWPGKQIHSHNYR 200

  Fly   177 SREVFEGKSVLVIGAGPSGMDLSNIISRTADRVTISHHLTDIG-QHSFFENVQQKPDVRELDEKG 240
            ..:.|:|:.|:|||...||.|:|..|:..|..|.|:....... :.|.:.|:...|.:..:.|.|
plant   201 VSDPFKGQVVIVIGYQSSGSDISRDIAILAKEVHIAAKSDAYAKESSIYSNLHFHPTIDRVYEDG 265

  Fly   241 A-FFVDGSYQEFDTVFFCTGYKYAFPFLTVDSGIYVEDNYVQELYKQCI-NIRNPSMALIGLPFY 303
            : .|.||.....|.:..||||||.||||.....:.||||.|..|||... ....|.::.||||..
plant   266 SVVFQDGKLIFADAIVHCTGYKYCFPFLETKGYVNVEDNRVGPLYKHVFPPALAPGLSFIGLPSM 330

  Fly   304 VCAAQMMDIQARFIMSYYNGSNELPSTEDMLKDTRDRMGKLWAEGLRKRHAHMLGPKQIDYFTDL 368
            .....|.:||:|::.|..:|..:|||.|.|::|......||.:.|:.||..|.|        ||.
plant   331 ALQFFMFEIQSRWVASVLSGRVKLPSEEQMMEDVIAFYAKLKSLGIPKRFTHFL--------TDP 387

  Fly   369 SQTAGVKNIKPVMTKLHNES-------SKCFNENLLHFREDNFAIL---DDETF 412
            ..|...:.:||....|.::|       .:|...::..:||:.:.|.   ||:.|
plant   388 QWTPMFEKLKPHEAVLISQSEYFNWIAEQCGCSSIERWREEQYNIAIKKDDDNF 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fmo-1	NP_611859.1	NADB_Rossmann	5..197	CDD:304358	75/212 (35%)
Fmo-1	NP_611859.1	NADB_Rossmann	185..>211	CDD:304358	11/25 (44%)
AT1G12130	NP_172677.1	PLN02172	1..463	CDD:215116	147/444 (33%)
AT1G12130	NP_172677.1	NADB_Rossmann	21..242	CDD:304358	77/226 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	150	1.000	Domainoid score	I1415
eggNOG	1	0.900	-	-		E1_COG2072
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H101446
Inparanoid	1	1.050	225	1.000	Inparanoid score	I1172
OMA	1	1.010	-	-		QHG55225
OrthoDB	1	1.010	-	-		D405736at2759
OrthoFinder	1	1.000	-	-		FOG0000093
OrthoInspector	1	1.000	-	-		mtm1034
orthoMCL	1	0.900	-	-		OOG6_100150
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X69
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.740