Protein Alignment Fmo-1 and Fmo2

DIOPT Version :9

• Sequence 1: NP_611859.1
• Gene: Fmo-1 / 37814
• FlyBaseID: FBgn0034943
• Length: 416
• Species: Drosophila melanogaster
• Sequence 2: NP_001347842.1
• Gene: Fmo2 / 55990
• MGIID: 1916776
• Length: 535
• Species: Mus musculus
• Alignment Length: 462
• Identity: 130/462 - (28%)
• Similarity: 210/462 - (45%)
• Gaps: 110/462 - (23%)

  Fly     4 VCIIGAGTAGLCCARHSIANGFETTVFELSDRIGGTWVYNEATGAVNGIDVHSSMYKNLRTNLPK 68
            |.:||||.:||...:..:..|.|.|.||.::.|||.|.:.|     |..|..:|:|:::.||..|
Mouse     5 VVVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGLWRFKE-----NVEDGRASIYRSVITNTSK 64

  Fly    69 EVMGFPDFEIGANEASYVRSDEICDFLNQYANHFDLKKHIKFDSYVIRVLQR-----KTKWQVLF 128
            |:..|.||.:..:..:::.:.::.::...:|..|||.|:|:|.:.||.|.:|     ..:|:|..
Mouse    65 EMSCFSDFPMPEDFPNFLHNSKLLEYFRIFAKKFDLLKYIQFQTTVISVKKRPDFASSGQWEVYT 129

  Fly   129 KDLVTNKIEFQYFDKVLVANGHYHTPN--YSQIPNMERFKGQFLHSHDFRSREVFEGKSVLVIGA 191
            :.  ..|.:...||.|:|.:||:..|:  ....|.:|||:||:.||.:::....||||.:||:|.
Mouse   130 QS--NGKEQRTVFDAVMVCSGHHIQPHLPLKSFPGIERFRGQYFHSREYKHPVGFEGKRILVVGI 192

  Fly   192 GPSGMDLSNIISRTADRVTIS--H------------HLTDIGQHSFF------------------ 224
            |.|..|:::.:|:||.:|.:|  |            :..|:..|:.|
Mouse   193 GNSAADIASELSKTAAQVFVSTRHGSWVMSRISEDGYPWDMVFHTRFSSMLRNVLPRTVVKWMME 257

  Fly   225 ---------EN----------------------------VQQKPDVRELDEKGAFFVDGSYQE-F 251
                     ||                            ::.|..|:||.|....|.||:.:| .
Mouse   258 QQMNRWFNHENYGLVPQNKYLMKEPVLNDDLPSRLLYGAIKVKTRVKELTETAVVFEDGTVEEDV 322

  Fly   252 DTVFFCTGYKYAFPFLTVDSGIYVEDNYVQELYKQCI--NIRNPSMALIGL--------PFYVCA 306
            |.:.|.|||.::|.||. ||.:.||||.| .|||...  ::..|::|.|||        |
Mouse   323 DIIVFATGYTFSFSFLE-DSLVKVEDNRV-SLYKAMFPPHLEKPTLACIGLIQPLGSIFP----- 380

  Fly   307 AQMMDIQARFIMSYYNGSNELPSTEDMLKDTRDRMGK---LWAEGLRKRHAHMLGPKQIDYFTDL 368
              .:::|||:....:.|...|||...|:.|..:|..|   |:.    |..:.:|....:||..:|
Mouse   381 --TVELQARWATRVFKGLCSLPSETTMMADIVERNEKRVNLFG----KSQSQILQTNYVDYLDEL 439

  Fly   369 SQTAGVK 375
            :...|.|
Mouse   440 ALEIGAK 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fmo-1	NP_611859.1	NADB_Rossmann	5..197	CDD:304358	65/198 (33%)
		NADB_Rossmann	185..>211	CDD:304358	10/25 (40%)
Fmo2	NP_001347842.1	K_oxygenase	2..532	CDD:330995	130/462 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2072
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	206	1.000	Inparanoid score	I3710
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55225
OrthoDB	1	1.010	-	-		D308082at33208
OrthoFinder	1	1.000	-	-		FOG0000093
OrthoInspector	1	1.000	-	-		mtm8771
orthoMCL	1	0.900	-	-		OOG6_100150
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2115
SonicParanoid	1	1.000	-	-		X69
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.810