DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fmo-1 and Foxred2

DIOPT Version :9

Sequence 1:NP_611859.1 Gene:Fmo-1 / 37814 FlyBaseID:FBgn0034943 Length:416 Species:Drosophila melanogaster
Sequence 2:NP_001017983.2 Gene:Foxred2 / 239554 MGIID:106315 Length:665 Species:Mus musculus


Alignment Length:348 Identity:76/348 - (21%)
Similarity:119/348 - (34%) Gaps:91/348 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 CIIGAGTAGLCCARHSIANGFETTVFELSDRIGGTW-----------VYNEATGAVNGIDVHSSM 58
            |::|||.|||..|......|.:..|||.....|..:           :....||..|........
Mouse    25 CVLGAGPAGLQMAAFLHRAGRDYEVFERESAPGSFFTRYPRHRKLISINKRHTGKANAEFNLRHD 89

  Fly    59 YKNLRTNLPKEVMG------FPDFEIGANEASYVRSDEICDFLNQYANHFDLKKHIKFDSYVIRV 117
            :.:|.::.|..:..      |||            :.::..:|..:|....|  |:.:::.:..|
Mouse    90 WNSLLSDDPHLLFRHYSQAYFPD------------ASDMVRYLGDFARRLGL--HVLYNTNITHV 140

  Fly   118 LQRK--TKWQVLFKDLVTNKIEFQYFDKVLVANGHYHTPNYSQIPNMERFKGQFLHSHDFRSREV 180
            ...|  ..|...:..|...|.:......:|||.| ...|.....|..|..:|....|.|   .|.
Mouse   141 TLDKDPQAWNGHYFILTDQKGQVYQCSVLLVATG-LAVPKLVDFPGSEYVEGYESVSVD---PED 201

  Fly   181 FEGKSVLVIGAGPSGMDLS-NIISRT-------ADRVTIS---HHLTDIG--QHSFFENVQQK-- 230
            |.|::||::|.|.|..:.: ||:..|       ..||.:|   |::.|:.  .:...:..|.|  
Mouse   202 FVGQNVLILGHGNSAFETAENILGVTNFVHMLSRSRVRLSWATHYVGDVRAINNGLLDTYQLKSL 266

  Fly   231 -----PDVREL----DEKGAFFV-------DGSYQE-------------------FDTVFFCTGY 260
                 .|:..|    |.||.|.|       :.|.|.                   :|.|..|.|:
Mouse   267 DGLLESDLEYLALVKDSKGKFHVTLKFLLENNSSQSADSIPLPEDDNDNFAMRVAYDRVIRCLGW 331

  Fly   261 KYAFPF----LTVDSGIYVEDNY 279
            .:.|..    |.:.||......|
Mouse   332 TFDFSIFDQSLRLSSGTEFSKKY 354

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fmo-1NP_611859.1 NADB_Rossmann 5..197 CDD:304358 48/210 (23%)
NADB_Rossmann 185..>211 CDD:304358 10/33 (30%)
Foxred2NP_001017983.2 Pyr_redox_3 25..240 CDD:290456 53/232 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 642..665
Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138 662..665
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2072
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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