DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fmo-1 and Fmo3

DIOPT Version :10

Sequence 1:NP_611859.1 Gene:Fmo-1 / 37814 FlyBaseID:FBgn0034943 Length:416 Species:Drosophila melanogaster
Sequence 2:NP_032056.1 Gene:Fmo3 / 14262 MGIID:1100496 Length:534 Species:Mus musculus


Alignment Length:457 Identity:131/457 - (28%)
Similarity:203/457 - (44%) Gaps:97/457 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 VCIIGAGTAGLCCARHSIANGFETTVFELSDRIGGTWVYNEATGAVNGIDVHSSMYKNLRTNLPK 68
            |.|||||.:||...|..:..|.|.|.||.||.:||.|.:::...     :..:|:|:::.||..|
Mouse     5 VAIIGAGVSGLAAIRSCLEEGLEPTCFERSDDVGGLWKFSDHIE-----EGRASIYQSVFTNSSK 64

  Fly    69 EVMGFPDFEIGANEASYVRSDEICDFLNQYANHFDLKKHIKFDSYVIRV-----LQRKTKWQVLF 128
            |:|.||||....:..:::...::.:::..:|...:|.|:|:|::.|..:     .....||:|..
Mouse    65 EMMCFPDFPYPDDFPNFMHHSKLQEYITSFAKEKNLLKYIQFETPVTSINKCPNFSTTGKWEVTT 129

  Fly   129 KDLVTNKIEFQYFDKVLVANGHY---HTPNYSQIPNMERFKGQFLHSHDFRSREVFEGKSVLVIG 190
            :.  ..|.|...||..::.:||:   |.|..| .|.:.||||:..||.|::...:::||.|||||
Mouse   130 EK--HGKKETAVFDATMICSGHHIFPHVPKDS-FPGLNRFKGKCFHSRDYKEPGIWKGKRVLVIG 191

  Fly   191 AGPSGMDLSNIISRTADRVTIS--------HHLTDIGQ----------HSFFEN----------- 226
            .|.||.|::..:|..|.:||||        ..:.|.|.          .:|.:|           
Mouse   192 LGNSGCDIAAELSHVAQKVTISSRSGSWVMSRVWDDGYPWDMVVLTRFQTFLKNNLPTAISDWWY 256

  Fly   227 ----------------------------------------VQQKPDVRELDEKGAFFVDGS-YQE 250
                                                    |..||:|:|..|..|.|.||: ::.
Mouse   257 TRQMNARFKHENYGLVPLNRTLRKEPVFNDELPARILCGMVTIKPNVKEFTETSAVFEDGTMFEA 321

  Fly   251 FDTVFFCTGYKYAFPFLTVDSGIYVEDNYVQELYKQCI--NIRNPSMALIGLPFYVCAA-QMMDI 312
            .|.|.|.|||.||:|||  |..|....|....|||...  .:..|:||:|||...:.|. .:.|:
Mouse   322 IDCVIFATGYGYAYPFL--DDSIIKSRNNEVTLYKGVFPPQLEKPTMAVIGLVQSLGATIPITDL 384

  Fly   313 QARFIMSYYNGSNELPSTEDMLKDTRDRMGKLWAEGLRKRHAHMLGPKQIDYFTDLSQTAGVKNI 377
            |||:......|:..|||..||:.|..::||:.:     |.:.:.. ..|.||...:.:.|.....
Mouse   385 QARWAAQVIKGTCTLPSVNDMMDDIDEKMGEKF-----KWYGNST-TIQTDYIVYMDELASFIGA 443

  Fly   378 KP 379
            ||
Mouse   444 KP 445

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fmo-1NP_611859.1 PLN02172 4..373 CDD:215116 128/449 (29%)
Fmo3NP_032056.1 FMO-like 2..533 CDD:395602 131/457 (29%)

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