DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment thoc5 and myo2

DIOPT Version :9

Sequence 1:	NP_611856.1	Gene:	thoc5 / 37810	FlyBaseID:	FBgn0034939	Length:	616	Species:	Drosophila melanogaster
Sequence 2:	NP_588114.1	Gene:	myo2 / 2539513	PomBaseID:	SPCC645.05c	Length:	1526	Species:	Schizosaccharomyces pombe

Alignment Length:	509	Identity:	107/509 - (21%)
Similarity:	198/509 - (38%)	Gaps:	156/509 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 QFDQLQKAIEGI--KEAKSKGQSTD----EARIATTLMFVALKHANREVKHKIKAGRDKLHLEKC 66
            |..:|:|.:|.:  |:...:.|:|.    ||::...|.  .:|...:|:::|         .|||
pombe  1087 QLPKLKKELESLNDKDQLYQLQATKNKELEAKVKECLN--NIKSLTKELENK---------EEKC 1140

  Fly    67 K----VDLSRLQLQ----NLLYEVSHLKKEIVRCQKFKSRDTSLELLSEAEYSSELPDMPNDAEE 123
            :    ..|..::||    |||.:||.|       :.:|.:...|:|..|.     |.|:..:.:|
pombe  1141 QNLSDASLKYIELQEIHENLLLKVSDL-------ENYKKKYEGLQLDLEG-----LKDVDTNFQE 1193

  Fly   124 LSSHKQHLHRLDCELRLRKALD-KQYSALLSSKQELLQDNLSHAQRYV-------SFAPALRTLQ 180
            ||...:.| ..:.|..||::.. |:..:|.||:.:.|.:.:|...:.|       |..|.|.  :
pombe  1194 LSKKHRDL-TFNHESLLRQSASYKEKLSLASSENKDLSNKVSSLTKQVNELSPKASKVPELE--R 1255

  Fly   181 SATKPLHDALQLSLDVE-WKLSAVVKYLPKPLYVLFIVLQSLQRVSEE-QSFTAEVVGYES---- 239
            ..|..:|:..||....| .|..|::                ..|.:|| :|..:|:   ||
pombe  1256 KITNLMHEYSQLGKTFEDEKRKALI----------------ASRDNEELRSLKSEL---ESKRKL 1301

  Fly   240 EAQMQELLKEKKCSTLNYRQTKKE-SGDREKIADKNNLDDSLAPHPLHICLTIGAAGSNQLVLQI 303
            |.:.|::|:|.|.:    |..:.| :..|.|:||..::...|:.                  :::
pombe  1302 EVEYQKVLEEVKTT----RSLRSEVTLLRNKVADHESIRSKLSE------------------VEM 1344

  Fly   304 RYFDFIKCATVWGQLNCSRNANGQGDTNFVHHLLRHLYPNDLGNELPIPGIQYELRSSDLTAEEC 368
            :..|..|      :||.:.::..:.:.. :|.|..|   ...|.|..||.::        |.|..
pombe  1345 KLVDTRK------ELNSALDSCKKREAE-IHRLKEH---RPSGKENNIPAVK--------TTEPV 1391

  Fly   369 VRYLKAKDYGKPFCWLQSMCSIATVNSSM-LYKH------ELNLNKNNKEIIDRIARRLNSWQRL 426
            ::.:..:         :::..:...|::. ||::      .|||.|:|                |
pombe  1392 LKNIPQR---------KTIFDLQQRNANQALYENLKRDYDRLNLEKHN----------------L 1431

  Fly   427 SQQIRGLTFKDIDLYSLQENIYPAGLSCSLVQWTAITHEELHSQISDALNSSSA 480
            .:|:.       :|...:.:..|.|.|   :|...:.|......:.|.:||..|
pombe  1432 EKQVN-------ELKGAEVSPQPTGQS---LQHVNLAHAIELKALKDQINSEKA 1475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
thoc5	NP_611856.1	FimP	42..392	CDD:286807	77/372 (21%)
myo2	NP_588114.1	COG5022	6..1516	CDD:227355	107/509 (21%)
		Myosin_N	25..>48	CDD:280832
		MYSc_class_II	91..743	CDD:276951
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000