DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3803 and COX15

DIOPT Version :9

Sequence 1:	NP_611855.1	Gene:	CG3803 / 37809	FlyBaseID:	FBgn0034938	Length:	393	Species:	Drosophila melanogaster
Sequence 2:	NP_200420.1	Gene:	COX15 / 835708	AraportID:	AT5G56090	Length:	457	Species:	Arabidopsis thaliana

Alignment Length:	410	Identity:	182/410 - (44%)
Similarity:	239/410 - (58%)	Gaps:	33/410 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LRLLQKRTNLIKLVVPGPRLHQTIAQTAIKEIPVIKPIST--PKSDKTVGRWFLGVSGMVFVAVG 64
            ||.|.|..|....     |...|:|..:.:....:|.:.|  |::.|.||.|..|.:..||..|.
plant    56 LRSLLKGQNASMF-----RRMSTVASISSESKEGLKLLVTGGPQAQKWVGIWLFGSAAWVFSMVV 115

  Fly    65 LGGVTRLTESGLSMVTWKLTGERMPRTQEEWVQEFNLYQQYPEYKLKNVNMTVEEFKFIFMMEYM 129
            ||||||||.|||||..||.|||..|.:.|.|.:||..|:|.||||..|..|.:|:||||:.|||.
plant   116 LGGVTRLTRSGLSMTDWKFTGEFPPLSDEAWAKEFEKYKQSPEYKRVNKGMNLEDFKFIYWMEYA 180

  Fly   130 HRMWGRAIGGFFLLPAVYFWRKGYFCAKTKKSVLLLGT-LIGL------QGLMGWYMVKSGLEDR 187
            ||||||.:|..|.||..||.||||.       .|.||. |.||      ||.:||:|||||||
plant   181 HRMWGRGLGIMFALPFSYFLRKGYI-------TLRLGVQLSGLFALGAGQGFIGWWMVKSGLE-- 236

  Fly   188 FQDPNDV--PRVSQYRLASHLAAAFVLYSLSLSKAMSLLI--PTNTFVIQAKKAFNIKGLTHLTK 248
             :.|::.  ||||.||||:||.:||.:|......|:|:::  |....:...:.|..:|.|.....
plant   237 -EPPSEYSQPRVSPYRLAAHLTSAFAIYCGLFWTALSVVMPEPPAESLAWVRGAAKVKKLALPVS 300

  Fly   249 AMVLLTAISGAFVAGLDAGLVYNSFPKMGDKWIPDDMWTFAPIQKNITENPTTVQFNHRILGIST 313
            .:|.:||||||||||.|||..:|:||||||.||||:::...|:.:|..||..|||.:||:|..:|
plant   301 LIVGITAISGAFVAGNDAGRAFNTFPKMGDTWIPDNIFEMKPLLRNFFENTATVQLDHRLLATTT 365

  Fly   314 VTLTTALWLVTRRMQLPKRANWAINAVVAMAWTQATLGVTTLLNYVPVPLATAHQSGSLILLSFA 378
            :.....:|..||::.:.......|.:.|.|...|.||||:|||:||||.|.:|||:|:|.||:..
plant   366 LIAIGTMWWFTRKLDIHPAVKALIGSTVGMTAVQVTLGVSTLLSYVPVSLGSAHQAGALTLLTLM 430

  Fly   379 LWLSHEVR-----LLKYLPK 393
            |.|:|.:|     |||.||:
plant   431 LLLNHTLRRPSPSLLKSLPQ 450

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3803	NP_611855.1	COX15-CtaA	49..379	CDD:280746	160/340 (47%)
COX15	NP_200420.1	COX15-CtaA	93..423	CDD:418569	159/339 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	290	1.000	Domainoid score	I364
eggNOG	1	0.900	-	-		E1_COG1612
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5848
Inparanoid	1	1.050	308	1.000	Inparanoid score	I750
OMA	1	1.010	-	-		QHG63145
OrthoDB	1	1.010	-	-		D1181324at2759
OrthoFinder	1	1.000	-	-		FOG0005070
OrthoInspector	1	1.000	-	-		oto3948
orthoMCL	1	0.900	-	-		OOG6_102761
Panther	1	1.100	-	-	LDO	PTHR23289
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3590
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840