DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3803 and Cox15

DIOPT Version :9

Sequence 1:	NP_611855.1	Gene:	CG3803 / 37809	FlyBaseID:	FBgn0034938	Length:	393	Species:	Drosophila melanogaster
Sequence 2:	NP_001028871.2	Gene:	Cox15 / 309391	RGDID:	1312043	Length:	414	Species:	Rattus norvegicus

Alignment Length:	369	Identity:	199/369 - (53%)
Similarity:	262/369 - (71%)	Gaps:	3/369 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 PRLHQTIAQTAIKEIPVIKPISTPKSDKTVGRWFLGVSGMVFVAVGLGGVTRLTESGLSMVTWKL 83
            |..:.||.:.|::.......:.:..:::.||||.|..||.|..||.|||||||||||||||.|.|
  Rat    44 PGQYGTITEVALQSGKGTVSLPSRAAERAVGRWLLVCSGTVAGAVILGGVTRLTESGLSMVDWHL 108

  Fly    84 TGERMPRT-QEEWVQEFNLYQQYPEYKLKNVNMTVEEFKFIFMMEYMHRMWGRAIGGFFLLPAVY 147
            ..|..|.| ||||..||..|||:||:|:.|.:||:.|||||:.|||.|||||||:|..::|||.|
  Rat   109 IKEMKPPTSQEEWEAEFQKYQQFPEFKILNHDMTLAEFKFIWYMEYSHRMWGRAVGLAYILPAAY 173

  Fly   148 FWRKGYFCAKTKKSVLLLGTLIGLQGLMGWYMVKSGLEDRFQDPNDVPRVSQYRLASHLAAAFVL 212
            |||||:.....|..||.|..|:..|||:||||||||||:: .:..|:|||||||||:||.:|.:|
  Rat   174 FWRKGWLNRGMKGRVLALCGLVCFQGLLGWYMVKSGLEEK-PESYDIPRVSQYRLAAHLGSALIL 237

  Fly   213 YSLSLSKAMSLLIPTNTFVIQAKKAFNIKGLTHLTKAMVLLTAISGAFVAGLDAGLVYNSFPKMG 277
            |..||..::|||:|.:. :.:.::...::.....|..:|.|||:|||||||||||||||||||||
  Rat   238 YCGSLWTSLSLLLPQHK-IPETRQLLWLRRFAGGTAGLVFLTALSGAFVAGLDAGLVYNSFPKMG 301

  Fly   278 DKWIPDDMWTFAPIQKNITENPTTVQFNHRILGISTVTLTTALWLVTRRMQLPKRANWAINAVVA 342
            :.|||:|:.||:||.||:.||||.|||:||:||:::||..|.|:.::||:.||:|...|...::|
  Rat   302 ESWIPEDLLTFSPILKNVFENPTMVQFDHRLLGVTSVTAITMLYFLSRRIPLPRRTKMAAVTLLA 366

  Fly   343 MAWTQATLGVTTLLNYVPVPLATAHQSGSLILLSFALWLSHEVR 386
            :|:.|..||::|||.|||.|||..||||||.|||.||||.:|:|
  Rat   367 LAYAQVALGISTLLMYVPTPLAATHQSGSLALLSGALWLMNELR 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3803	NP_611855.1	COX15-CtaA	49..379	CDD:280746	188/330 (57%)
Cox15	NP_001028871.2	COX15-CtaA	74..400	CDD:280746	186/327 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334389
Domainoid	1	1.000	366	1.000	Domainoid score	I901
eggNOG	1	0.900	-	-		E1_COG1612
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5848
Inparanoid	1	1.050	387	1.000	Inparanoid score	I1949
OMA	1	1.010	-	-		QHG63145
OrthoDB	1	1.010	-	-		D1181324at2759
OrthoFinder	1	1.000	-	-		FOG0005070
OrthoInspector	1	1.000	-	-		oto96944
orthoMCL	1	0.900	-	-		OOG6_102761
Panther	1	1.100	-	-	LDO	PTHR23289
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3590
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770