DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fzr2 and CDC20.3

DIOPT Version :9

Sequence 1:	NP_611854.1	Gene:	fzr2 / 37808	FlyBaseID:	FBgn0034937	Length:	451	Species:	Drosophila melanogaster
Sequence 2:	NP_198060.2	Gene:	CDC20.3 / 832766	AraportID:	AT5G27080	Length:	442	Species:	Arabidopsis thaliana

Alignment Length:	451	Identity:	160/451 - (35%)
Similarity:	243/451 - (53%)	Gaps:	50/451 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 KEDIDLRCIPTRAGNHWN-RNFVNAPGDSNVYESSVYSCLLRNEFLDENITSLENCEQTAQVHAQ 82
            |:::| |.||.|:...:: .|:....|              |...:|| |||........|:...
plant    19 KQNLD-RFIPNRSAMDFDFANYALTQG--------------RKRNVDE-ITSASRKAYMTQLAVV 67

  Fly    83 TDDFRDRHNRIFGFASGSSSPVRTPFANISES-SQRLLSIFKRPMRRLPRRPYKILDAPELQDDF 146
            .:..|   .||..|   .:.|.....:|.|:| .|...|:  :|.|.:|:...::||||.|.|||
plant    68 MNQNR---TRILAF---RNKPKALLSSNHSDSPHQNPKSV--KPRRYIPQNSERVLDAPGLMDDF 124

  Fly   147 YLNLIDWSSKNTLAVGLGCSVYLWSAVSGQVTRLCDFNNEDNLITAVSWHGEGRQVAIGTQSGYV 211
            ||||:||.|.|.||:.||.:||||.|.||..:.|...:.:...:|:::|..:|..:|:|..:..|
plant   125 YLNLLDWGSANVLAIALGDTVYLWDASSGSTSELVTIDEDKGPVTSINWTQDGLDLAVGLDNSEV 189

  Fly   212 TIWDAENQKQINRL-EEHSARVTALAWCGNRLASGSRDRSILQRDIRNPPTHITRCLRGHKLEVC 275
            .:||..:.:|:..| ..|.:||.:|||..:.|.:|..|..|:..|:|...:.:...| ||..|||
plant   190 QLWDFVSNRQVRTLIGGHESRVGSLAWNNHILTTGGMDGKIVNNDVRIRSSIVGTYL-GHTEEVC 253

  Fly   276 GLQWSPSNRYLASGGSDNRLLVW----------TDDWPEPIYAFDEHKAVVKALGWSPHKSGLLA 330
            ||:||.|.:.|||||:.|.:.:|          |..|   ::.|:||.|.|:||.|.|.::.|||
plant   254 GLKWSESGKKLASGGNYNVVHIWDHRSVASSKPTRQW---LHRFEEHTAAVRALAWCPFQATLLA 315

  Fly   331 SGGGSADRCLRFWNVLTGKLVKCINTGAQISNLAWARDSRELVTTHGHAQPQVIAWRYPSLKQMA 395
            :|||..|..::|||..||..:..:.||:|:.:|.|::..|||:::||..|.|:..|:|||:.:||
plant   316 TGGGVGDGKIKFWNTHTGACLNSVETGSQVCSLLWSQRERELLSSHGFTQNQLTLWKYPSMSKMA 380

  Fly   396 RLSGHTQRVLHLSVSPDNESIVTGGADETLRFWTVF------TKQKISKEPNSVLRLFKGI 450
            .|:|||.|||.::.||:..::.:...||.||.|.||      ||:..||   :.|.||..:
plant   381 ELNGHTSRVLFMAQSPNGCTVASAAGDENLRLWNVFGEPPKTTKKAASK---NYLELFSHV 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fzr2	NP_611854.1	WD40	<101..439	CDD:225201	137/355 (39%)
		WD40 repeat	149..185	CDD:293791	18/35 (51%)
		WD40	190..446	CDD:295369	102/272 (38%)
		WD40 repeat	190..227	CDD:293791	10/37 (27%)
		WD40 repeat	233..269	CDD:293791	10/35 (29%)
		WD40 repeat	274..310	CDD:293791	16/45 (36%)
		WD40 repeat	317..355	CDD:293791	16/37 (43%)
		WD40 repeat	360..398	CDD:293791	15/37 (41%)
		WD40 repeat	404..436	CDD:293791	13/37 (35%)
CDC20.3	NP_198060.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0305
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54440
OrthoDB	1	1.010	-	-		D1220675at2759
OrthoFinder	1	1.000	-	-		FOG0000628
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.830