Protein Alignment fzr2 and cort

DIOPT Version :9

• Sequence 1: NP_611854.1
• Gene: fzr2 / 37808
• FlyBaseID: FBgn0034937
• Length: 451
• Species: Drosophila melanogaster
• Sequence 2: NP_001260144.1
• Gene: cort / 33937
• FlyBaseID: FBgn0000351
• Length: 483
• Species: Drosophila melanogaster
• Alignment Length: 513
• Identity: 101/513 - (19%)
• Similarity: 185/513 - (36%)
• Gaps: 170/513 - (33%)

  Fly    25 RCIPT---RAGNHWNRNFVNAPGDSNVYESSVYSCLLRNEFLDENITS--------LENCEQTAQ 78
            |.||.   |....:|..::....:.::.|:.|            .:|:        :.|..:|
  Fly    55 RFIPNRFERENIEFNLKYIGKRKERDILETGV------------TLTASYWRQSGFISNINRT-- 105

  Fly    79 VHAQTDDFRDRHNRIFGFASGSSSPVRTPFANISESSQRLLSIFKRPMRRLPR-RPYKILDA--- 139
                   |.....|:|.|:|...:..|....:.::|..        |..  || |||.|.:|
  Fly   106 -------FGIGERRLFQFSSQQGTRSRVVDNDSADSDW--------PCN--PRARPYAIQNATHE 153

  Fly   140 -PELQDDFYLNLIDWSSKNTLAVGLGCSVYLWSAVSGQVTRLCDFNNEDNLI------TAVSWHG 197
             |.:......|::||||...:|:..|..|.||..:           :|..::      |::.:..
  Fly   154 MPGICSPVDYNMMDWSSGGMVAMSSGQDVMLWRNL-----------DESTMVFSVESPTSLKYSP 207

  Fly   198 EGRQVAIGTQS-GY--VTIWDAENQKQI-----NRLEEHSARVTALAWC--GNRLASGSRDRSIL 252
            :|:.:|||... .|  :.:|:..:..:.     ....:....::.:.|.  |..:..|::...|:
  Fly   208 DGKHLAIGCMDRNYPVLDLWEVRSPTEFLVSYRKLFFKSMGYISCIEWSHDGKEVICGTQCGVII 272

  Fly   253 QRDIRNPPTHITRCLRGHKLEVCGLQWSPSNRYLASGGSDNRLLVW----------------TDD 301
            .  :..|..:....||.|:..|..::::|:::|.||..:|.::.::                ..|
  Fly   273 V--LAMPTLNTLMQLREHRHTVKKMKFAPTHKYFASSDTDGKIFIFDAVLKVRLLKLDGRSIVFD 335

  Fly   302 W--------------PEPIYAFD-------------EHKAVVKALGWSPHKSGLLASGGGSADRC 339
            |              |..|:.|:             :.:.|:|.|.:|.
  Fly   336 WHPWTGEDLAVAERSPASIFIFNIPRRQFVASYRRRDDRIVIKTLTYSK---------------- 384

  Fly   340 LRFWNVLTGKLVKCINTGAQISNLAWARDSRELVTTHGHAQPQVIAWRYPSLKQMARLSGHTQR- 403
                  :||:|:  :|        ...||..:|..    .:..|:|    ||.::..|..|..|
  Fly   385 ------ITGELL--VN--------VIRRDDADLAV----CEILVLA----SLNRVVDLMSHQDRG 425

  Fly   404 VLHLSVSPDNESIVTGGADETLRFWTVF----------TKQKISKEPNSVLRLFKGIR 451
            .|.|..:||...|.|||.|:|...|..|          .:::.:|:..|.|.|:||||
  Fly   426 TLFLMWNPDGTKIATGGLDDTFSLWNFFPTYKREAILRKQEQKAKDKCSSLSLYKGIR 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fzr2	NP_611854.1	WD40	<101..439	CDD:225201	78/412 (19%)
		WD40 repeat	149..185	CDD:293791	10/35 (29%)
		WD40	190..446	CDD:295369	59/325 (18%)
		WD40 repeat	190..227	CDD:293791	7/50 (14%)
		WD40 repeat	233..269	CDD:293791	6/37 (16%)
		WD40 repeat	274..310	CDD:293791	10/65 (15%)
		WD40 repeat	317..355	CDD:293791	6/37 (16%)
		WD40 repeat	360..398	CDD:293791	7/37 (19%)
		WD40 repeat	404..436	CDD:293791	12/41 (29%)
cort	NP_001260144.1	WD40	<166..453	CDD:225201	65/339 (19%)
		WD40	166..451	CDD:295369	64/337 (19%)
		WD40 repeat	201..244	CDD:293791	7/42 (17%)
		WD40 repeat	251..287	CDD:293791	6/37 (16%)
		WD40 repeat	292..326	CDD:293791	6/33 (18%)
		WD40 repeat	334..369	CDD:293791	5/34 (15%)
		WD40 repeat	377..419	CDD:293791	14/81 (17%)
		WD40 repeat	427..466	CDD:293791	12/38 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0305
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR19918
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910