Protein Alignment fzr2 and srw1

DIOPT Version :10

• Sequence 1: NP_611854.1
• Gene: fzr2 / 37808
• FlyBaseID: FBgn0034937
• Length: 451
• Species: Drosophila melanogaster
• Sequence 2: NP_594674.1
• Gene: srw1 / 2542824
• PomBaseID: SPAC144.13C
• Length: 556
• Species: Schizosaccharomyces pombe
• Alignment Length: 479
• Identity: 181/479 - (37%)
• Similarity: 254/479 - (53%)
• Gaps: 78/479 - (16%)

  Fly    25 RCIPTRAGNH--WNRNFVNAPG------------DSNVYESSVYSCLLRNEFLDENITSLENCE- 74
            |.||:|..:.  |. .|....|            |.|      ::.|||:|....|..:..|..
pombe    75 RFIPSRDASTELWT-GFTKVEGPLTPVKKKQSVADRN------FTTLLRSELFGSNDETFNNSPI 132

  Fly    75 ---------QTAQVHAQTDDF-----------------------------------RDRHNRIFG 95
                     .|.:..:..||.                                   |||:...:|
pombe   133 ATPNTTIGVSTPRTDSGIDDIELTQRTPPSSSHTSSSILQNTPVTPSRKIFHYLSPRDRNKSSYG 197

  Fly    96 -FASGSSSPVRT-----PFANISESSQRLLSIFKRPMRRLPRRPYKILDAPELQDDFYLNLIDWS 154
             .|....:|.||     |..:|::.   |:|..:...|.||..||::||||.|..||||||:||.
pombe   198 KKAQYQDNPNRTIYSLSPVRSITKD---LISASRLEGRELPSIPYRVLDAPGLAGDFYLNLLDWG 259

  Fly   155 SKNTLAVGLGCSVYLWSAVSGQVTRLCDFNNEDNLITAVSWHGEGRQVAIGTQSGYVTIWDAENQ 219
            ..|.|||.|...|||||.:|.:||.:.:|...|. :|::.|...|..:|:||.:|.|.||||...
pombe   260 QCNMLAVALASRVYLWSGISSEVTVMHNFYPTDT-VTSLRWVQRGTHLAVGTHNGSVEIWDAATC 323

  Fly   220 KQINRLEEHSARVTALAWCGNRLASGSRDRSILQRDIRNPPTHITRCLRGHKLEVCGLQWSPSNR 284
            |:...:..|:.||.||:|..:.|:||.||..||.||:| .|.|..|.|..|:.|||||:|:.:..
pombe   324 KKTRTMSGHTERVGALSWNDHVLSSGGRDNHILHRDVR-APEHYFRVLTAHRQEVCGLEWNSNEN 387

  Fly   285 YLASGGSDNRLLVWTDDWPEPIYAFDEHKAVVKALGWSPHKSGLLASGGGSADRCLRFWNVLTGK 349
            .|||||:||.|:||.....:|:|:|..|.|.|||:.||||:.|:||||||:|||.::.||...|.
pombe   388 LLASGGNDNALMVWDKFEEKPLYSFHNHIAAVKAITWSPHQRGILASGGGTADRTIKLWNTQRGS 452

  Fly   350 LVKCINTGAQISNLAWARDSRELVTTHGHAQPQVIAWRYPSLKQMARLSGHTQRVLHLSVSPDNE 414
            ::..|:||:|:.||.|::.:.|.::|||..:.:|..|.|||:.::..|.|||.|||:|::||:.|
pombe   453 MLHNIDTGSQVCNLLWSKQTNEFISTHGFMENEVALWNYPSVSRVGTLKGHTDRVLYLAMSPNGE 517

  Fly   415 SIVTGGADETLRFWTVF-TKQKIS 437
            :||||.||||||||.:| :|.|.|
pombe   518 NIVTGAADETLRFWKLFDSKSKHS 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fzr2	NP_611854.1	WD40 repeat	149..185	CDD:293791	18/35 (51%)
		WD40	<159..436	CDD:441893	130/277 (47%)
		WD40 repeat	190..227	CDD:293791	13/36 (36%)
		WD40 repeat	233..269	CDD:293791	17/35 (49%)
		WD40 repeat	274..310	CDD:293791	17/35 (49%)
		WD40 repeat	317..355	CDD:293791	19/37 (51%)
		WD40 repeat	360..398	CDD:293791	12/37 (32%)
		WD40 repeat	404..436	CDD:293791	20/32 (63%)
srw1	NP_594674.1	WD40	<290..533	CDD:441893	115/244 (47%)
		WD40 repeat	295..331	CDD:293791	13/35 (37%)
		WD40 repeat	336..370	CDD:293791	17/34 (50%)
		WD40 repeat	378..413	CDD:293791	16/34 (47%)
		WD40 repeat	419..455	CDD:293791	20/35 (57%)
		WD40 repeat	463..501	CDD:293791	12/37 (32%)
		WD40 repeat	507..531	CDD:293791	16/23 (70%)