Protein Alignment fzr2 and mfr1

DIOPT Version :10

• Sequence 1: NP_611854.1
• Gene: fzr2 / 37808
• FlyBaseID: FBgn0034937
• Length: 451
• Species: Drosophila melanogaster
• Sequence 2: NP_595081.1
• Gene: mfr1 / 2540043
• PomBaseID: SPBC1198.12
• Length: 421
• Species: Schizosaccharomyces pombe
• Alignment Length: 441
• Identity: 200/441 - (45%)
• Similarity: 270/441 - (61%)
• Gaps: 43/441 - (9%)

  Fly    25 RCIPTR-AGNHWNRNF------VNAPGDSNVYESSVYSCLLRNEFLDENITSLE----------- 71
            |.||.| ..|.:|.:|      |.:.| ||:...:  |..::.:|::  :.|:|
pombe     4 RFIPIRNVSNEFNFSFQSFKECVLSHG-SNLRRKT--SGTIQRQFME--LLSMELFGSQASRSRA 63

  Fly    72 --NCEQTAQVHAQTDDFRDRHNRIFGFASGSSSPVRTPFANISESSQRLLSIFKRPMRRLPRRPY 134
              ..|...::..:..|..||       .|.|.||       ||..||.:|...::|.|..|:.||
pombe    64 FYYGEDKRKIEKKMLDTPDR-------KSYSLSP-------ISPQSQDMLRQPQKPKRAFPKTPY 114

  Fly   135 KILDAPELQDDFYLNLIDWSSKNTLAVGLGCSVYLWSAVSGQVTRLCDFNNEDNLITAVSWHGEG 199
            ||||||.|::||||||:||...|.|||||..|:|||||.||:|.:|.|| ...|.:|:|.|.|:|
pombe   115 KILDAPYLKNDFYLNLLDWGQSNVLAVGLASSIYLWSAASGKVVQLHDF-GATNHVTSVLWTGKG 178

  Fly   200 RQVAIGTQSGYVTIWDAENQKQINRLEEHSARVTALAWCGNRLASGSRDRSILQRDIRNPPTHIT 264
            .|:|:||.||.:.|||.|:.|.:..|:.||.||.||||..|.|.||.:|..||..|:|.|.. ..
pombe   179 TQLAVGTDSGVIYIWDIESTKSVRSLKGHSERVAALAWNDNTLTSGGKDEVILHHDLRAPGC-CA 242

  Fly   265 RCLRGHKLEVCGLQWSPSNRYLASGGSDNRLLVWTDDWPEPIYAFDEHKAVVKALGWSPHKSGLL 329
            ..::.|:.|:|||||..|...|||||:||.|.||......|::.|:||.|.|||:|||||:.|:|
pombe   243 EMMKVHEQEICGLQWDRSLGQLASGGNDNNLFVWDYRSSRPLHKFEEHTAAVKAIGWSPHQRGIL 307

  Fly   330 ASGGGSADRCLRFWNVLTGKLVKCINTGAQISNLAWARDSRELVTTHGHAQPQVIAWRYPSLKQM 394
            |||||:.||||...|.|||:|...::||:|:.|:||::.|.|:|||||.|:.||..|:|||||.:
pombe   308 ASGGGTIDRCLTIHNTLTGRLQNKLDTGSQVCNMAWSKTSNEIVTTHGFAKNQVSLWKYPSLKNI 372

  Fly   395 ARLSGHTQRVLHLSVSPDNESIVTGGADETLRFWTVFTKQKISKEPNSVLR 445
            |.|:.||.|||:||:|||.:|||||..|||||||.:|.|:  .||.::::|
pombe   373 ANLTAHTNRVLYLSMSPDGQSIVTGAGDETLRFWKLFNKK--PKEESTLIR 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fzr2	NP_611854.1	WD40 repeat	149..185	CDD:293791	22/35 (63%)
		WD40	<159..436	CDD:441893	148/276 (54%)
		WD40 repeat	190..227	CDD:293791	17/36 (47%)
		WD40 repeat	233..269	CDD:293791	14/35 (40%)
		WD40 repeat	274..310	CDD:293791	17/35 (49%)
		WD40 repeat	317..355	CDD:293791	23/37 (62%)
		WD40 repeat	360..398	CDD:293791	20/37 (54%)
		WD40 repeat	404..436	CDD:293791	21/31 (68%)
mfr1	NP_595081.1	WD40	<138..408	CDD:441893	146/271 (54%)
		WD40 repeat	169..206	CDD:293791	17/36 (47%)
		WD40 repeat	212..247	CDD:293791	14/35 (40%)
		WD40 repeat	252..288	CDD:293791	17/35 (49%)
		WD40 repeat	295..333	CDD:293791	23/37 (62%)
		WD40 repeat	338..376	CDD:293791	20/37 (54%)
		WD40 repeat	382..408	CDD:293791	19/25 (76%)