Protein Alignment fzr2 and fzr

DIOPT Version :10

• Sequence 1: NP_611854.1
• Gene: fzr2 / 37808
• FlyBaseID: FBgn0034937
• Length: 451
• Species: Drosophila melanogaster
• Sequence 2: XP_061500042.1
• Gene: fzr / 1281339
• VectorBaseID: AGAMI1_001795
• Length: 496
• Species: Anopheles gambiae
• Alignment Length: 507
• Identity: 239/507 - (47%)
• Similarity: 318/507 - (62%)
• Gaps: 67/507 - (13%)

  Fly     1 MFQSEYQQRLL----PGV----AVGKKEDIDLRCIPTRAGNHWNRNFV--------NAPGDS--- 46
            ||..||::|.:    |..    :..:......|.||.||.|:|..||.        |:|..:
Mosquito     1 MFSPEYEKRYMQLRSPAARSLFSASESSSAHDRFIPCRANNNWTTNFATISTKSNENSPQSTKKQ 65

  Fly    47 -----NVYESSVYSCLLRNEFLDENITSLE--------------------------------NCE 74
                 |..:|..|||||:||.|...|..::                                |.:
Mosquito    66 RDCGENARDSLAYSCLLKNELLGTGIDDVKLVADDKNGSGGGGGGGGGGGGGGGAGGGGLHANSQ 130

  Fly    75 QTAQVHAQTDDFRDRHNRIFGFASGSSSPVRTPFANISESSQRLLSIFKRPMRRLPRRPYKILDA 139
            :|.....|:...:|.:.:    ...|.|||       |..||:||...::..|::.:.|:|:|||
Mosquito   131 RTGLFKYQSPTKQDYNEQ----CPYSLSPV-------SIKSQKLLRSPRKATRKISKIPFKVLDA 184

  Fly   140 PELQDDFYLNLIDWSSKNTLAVGLGCSVYLWSAVSGQVTRLCDFNNEDNLITAVSWHGEGRQVAI 204
            |||||||||||:|||::|.||||||..||||||.:.|||||||.:::.|.||:|||...|.|:|:
Mosquito   185 PELQDDFYLNLVDWSAQNVLAVGLGSCVYLWSACTSQVTRLCDLSSDSNTITSVSWSERGHQLAV 249

  Fly   205 GTQSGYVTIWDAENQKQINRLEEHSARVTALAWCGNRLASGSRDRSILQRDIRNPPTHITRCLRG 269
            |||.||||:||....||:|:|:.|||||.||||.|:.|:||||||.|:|||.|.|.....|.|.|
Mosquito   250 GTQHGYVTVWDVAASKQVNKLQGHSARVGALAWNGDVLSSGSRDRLIMQRDTRTPSQVPERRLAG 314

  Fly   270 HKLEVCGLQWSPSNRYLASGGSDNRLLVWTDDWPEPIYAFDEHKAVVKALGWSPHKSGLLASGGG 334
            |:.|||||:|||.|:||||||:||||.||......|::::.||.|.|||:.||||..||||||||
Mosquito   315 HRQEVCGLKWSPDNQYLASGGNDNRLYVWNQHSSTPVHSYSEHMAAVKAIAWSPHHHGLLASGGG 379

  Fly   335 SADRCLRFWNVLTGKLVKCINTGAQISNLAWARDSRELVTTHGHAQPQVIAWRYPSLKQMARLSG 399
            :||||:||||.|||:.::|::||:|:.||||::.|.|||:|||::|.|::.|:||||.|:|:|:|
Mosquito   380 TADRCIRFWNTLTGQPMQCVDTGSQVCNLAWSKHSSELVSTHGYSQNQILVWKYPSLTQVAKLTG 444

  Fly   400 HTQRVLHLSVSPDNESIVTGGADETLRFWTVFTKQKISKEPNSVLRLFKGIR 451
            |:.|||:|::|||.|:||||..|||||||.||:|.:..||..|||.||..||
Mosquito   445 HSYRVLYLALSPDGEAIVTGAGDETLRFWNVFSKARSQKENKSVLNLFTNIR 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fzr2	NP_611854.1	WD40 repeat	149..185	CDD:293791	25/35 (71%)
		WD40	<159..436	CDD:441893	168/276 (61%)
		WD40 repeat	190..227	CDD:293791	21/36 (58%)
		WD40 repeat	233..269	CDD:293791	20/35 (57%)
		WD40 repeat	274..310	CDD:293791	21/35 (60%)
		WD40 repeat	317..355	CDD:293791	26/37 (70%)
		WD40 repeat	360..398	CDD:293791	20/37 (54%)
		WD40 repeat	404..436	CDD:293791	21/31 (68%)
fzr	XP_061500042.1	None