Protein Alignment fzr2 and fzr1b

DIOPT Version :10

• Sequence 1: NP_611854.1
• Gene: fzr2 / 37808
• FlyBaseID: FBgn0034937
• Length: 451
• Species: Drosophila melanogaster
• Sequence 2: XP_003197866.1
• Gene: fzr1b / 100148604
• ZFINID: ZDB-GENE-131120-69
• Length: 485
• Species: Danio rerio
• Alignment Length: 459
• Identity: 226/459 - (49%)
• Similarity: 308/459 - (67%)
• Gaps: 47/459 - (10%)

  Fly    25 RCIPTRAGNHWNRNFVNAPGDSNVY-----------------ESSVYSCLLRNEFLDENITSLEN 72
            |.||||||::|:.||..|  :.|.:                 ::..|:.|||||.|...|.::.:
Zfish    42 RFIPTRAGSNWSINFHYA--NENCWSPNQNQRAKDASTDTGKDAVAYAALLRNELLGAGIETVPD 104

  Fly    73 CEQTAQVHAQTDDFR------DRHNRIFGFASGSSSPVRTPFAN---------ISESSQRLLSIF 122
                    ..|||.|      |.|: :|.:...:.   |.||.|         :|..|.:||...
Zfish   105 --------PHTDDRRHTILTQDTHS-LFRYTIHTK---RVPFDNEISPYSLSPLSNKSHKLLRSP 157

  Fly   123 KRPMRRLPRRPYKILDAPELQDDFYLNLIDWSSKNTLAVGLGCSVYLWSAVSGQVTRLCDFNNED 187
            ::|.|::.:.|:|:||||||||||||||:|||:.|.|:||||..||||||.:.|||||||.:.:.
Zfish   158 RKPARKISKIPFKVLDAPELQDDFYLNLVDWSAGNLLSVGLGACVYLWSACTSQVTRLCDLSVDG 222

  Fly   188 NLITAVSWHGEGRQVAIGTQSGYVTIWDAENQKQINRLEEHSARVTALAWCGNRLASGSRDRSIL 252
            :.:|:|.|:..|..||:||..|:|.||||...:::..||.|||||.||||.|.:|:||||||.||
Zfish   223 DSVTSVCWNERGSLVAVGTHKGFVQIWDAAGGRKLTSLEGHSARVGALAWNGEQLSSGSRDRVIL 287

  Fly   253 QRDIRNPPTHITRCLRGHKLEVCGLQWSPSNRYLASGGSDNRLLVWTDDWPEPIYAFDEHKAVVK 317
            |||:|.||. :.|.|:||:.|||||:|||.:::|||||:||:||||......|:..:.:|.|.||
Zfish   288 QRDVRTPPP-VERRLQGHRQEVCGLKWSPDHQHLASGGNDNKLLVWNSSSLLPVQQYSDHLAAVK 351

  Fly   318 ALGWSPHKSGLLASGGGSADRCLRFWNVLTGKLVKCINTGAQISNLAWARDSRELVTTHGHAQPQ 382
            |:.||||:.||||||||:|||||||||.|||:.::..:||:|:.||||::.:.|||:|||::|.|
Zfish   352 AIAWSPHQHGLLASGGGTADRCLRFWNTLTGQALQSTDTGSQVCNLAWSKHANELVSTHGYSQNQ 416

  Fly   383 VIAWRYPSLKQMARLSGHTQRVLHLSVSPDNESIVTGGADETLRFWTVFTKQKISKEPNSVLRLF 447
            ::.|:||||.|:|:|:||:.|||:|:||||.|:||||..|||||||.||:|.:.:||..|||.||
Zfish   417 ILVWKYPSLTQVAKLTGHSYRVLYLAVSPDGEAIVTGAGDETLRFWNVFSKTRCTKESKSVLNLF 481

  Fly   448 KGIR 451
            ..||
Zfish   482 TRIR 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fzr2	NP_611854.1	WD40 repeat	149..185	CDD:293791	24/35 (69%)
		WD40	<159..436	CDD:441893	160/276 (58%)
		WD40 repeat	190..227	CDD:293791	15/36 (42%)
		WD40 repeat	233..269	CDD:293791	22/35 (63%)
		WD40 repeat	274..310	CDD:293791	19/35 (54%)
		WD40 repeat	317..355	CDD:293791	26/37 (70%)
		WD40 repeat	360..398	CDD:293791	19/37 (51%)
		WD40 repeat	404..436	CDD:293791	22/31 (71%)
fzr1b	XP_003197866.1	WD40	<193..464	CDD:441893	157/271 (58%)
		WD40 repeat	225..262	CDD:293791	15/36 (42%)
		WD40 repeat	268..303	CDD:293791	22/35 (63%)
		WD40 repeat	308..343	CDD:293791	19/34 (56%)
		WD40 repeat	351..389	CDD:293791	26/37 (70%)
		WD40 repeat	394..432	CDD:293791	19/37 (51%)
		WD40 repeat	438..479	CDD:293791	26/40 (65%)