DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Stoml2 and PHB2

DIOPT Version :9

Sequence 1:	NP_001261161.1	Gene:	Stoml2 / 37807	FlyBaseID:	FBgn0034936	Length:	366	Species:	Drosophila melanogaster
Sequence 2:	NP_011747.2	Gene:	PHB2 / 853146	SGDID:	S000003463	Length:	310	Species:	Saccharomyces cerevisiae

Alignment Length:	254	Identity:	57/254 - (22%)
Similarity:	100/254 - (39%)	Gaps:	74/254 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 RFH----RILDPGLNILVPVADKIKYVQSLKEIAIDV---PKQSAI---TSD----NVT---LSI 106
            |.|    ||.:.|.:.:.|..|        ..|..||   |:..|.   |.|    |:|   ||.
Yeast    72 RIHGVSSRIFNEGTHFIFPWLD--------TPIIYDVRAKPRNVASLTGTKDLQMVNITCRVLSR 128

  Fly   107 DGVLYLRIIDPYKASYGVEDPEFAITQLAQTTMRSELGKMSMDKVFRERESLNVSIVDSINKASE 171
            ..|:.|..|  |: :.|.:..|..:..:....:::.:.:.:..::..:||.::..|.:::.:.:.
Yeast   129 PDVVQLPTI--YR-TLGQDYDERVLPSIVNEVLKAVVAQFNASQLITQREKVSRLIRENLVRRAS 190

  Fly   172 AWGIACLRYEIRDIRLP--------TRVHEAMQM-QVEAER----------RKRAAILESEG-VR 216
            .:.|.     :.|:.:.        |...||.|: |.:|:|          .|:..::.::| .:
Yeast   191 KFNIL-----LDDVSITYMTFSPEFTNAVEAKQIAQQDAQRAAFVVDKARQEKQGMVVRAQGEAK 250

  Fly   217 EAEINIAEGKRKSR----------------ILASEAERQEHINKASGEAAAIIAVADAR 259
            .||: |.|..:|||                ||||...|....|    ||..:..|.|||
Yeast   251 SAEL-IGEAIKKSRDYVELKRLDTARDIAKILASSPNRVILDN----EALLLNTVVDAR 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Stoml2	NP_001261161.1	PHB	41..199	CDD:214581	33/165 (20%)
		SPFH_paraslipin	80..188	CDD:259811	22/120 (18%)
		Band_7_C	266..326	CDD:292817
PHB2	NP_011747.2	SPFH_prohibitin	58..252	CDD:259799	38/195 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0330
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810