DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Stoml2 and Stoml1

DIOPT Version :9

Sequence 1:	NP_001261161.1	Gene:	Stoml2 / 37807	FlyBaseID:	FBgn0034936	Length:	366	Species:	Drosophila melanogaster
Sequence 2:	NP_081218.3	Gene:	Stoml1 / 69106	MGIID:	1916356	Length:	399	Species:	Mus musculus

Alignment Length:	171	Identity:	46/171 - (26%)
Similarity:	72/171 - (42%)	Gaps:	14/171 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 SWIPSQSRRGKAST----------PIN--MCVMFVPQQEAWVVERMGRFHRILDPGLNILVPVAD 76
            || ||....|..|.          ||:  ..:..||..|..:|.|:||......||:.:|:|..|
Mouse    49 SW-PSCLCHGLVSVLGFLLLLLTFPISGWFALKIVPTYERMIVFRLGRIRNPQGPGMVLLLPFID 112

  Fly    77 KIKYVQSLKEIAIDVPKQSAITSDNVTLSIDGVLYLRIIDPYKASYGVEDPEFAITQLAQTTMRS 141
            ..:.| .|:..|.:||.....:.|...||:...:..||.||..:...|:|...|....|...|..
Mouse   113 SFQRV-DLRTRAFNVPPCKLASKDGAVLSVGADVQFRIWDPVLSVMAVKDLNTATRMTAHNAMTK 176

  Fly   142 ELGKMSMDKVFRERESLNVSIVDSINKASEAWGIACLRYEI 182
            .|.:..:.::..|:..:...::..||..:.|||:...|.|:
Mouse   177 ALLRRPLQEIQMEKLKIGDQLLLEINDVTRAWGLEVDRVEL 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Stoml2	NP_001261161.1	PHB	41..199	CDD:214581	38/142 (27%)
		SPFH_paraslipin	80..188	CDD:259811	26/103 (25%)
		Band_7_C	266..326	CDD:292817
Stoml1	NP_081218.3	Tyrosine-type lysosomal sorting signal. /evidence=ECO:0000250\|UniProtKB:Q9UBI4, ECO:0000255	6..10
		PHB	77..217	CDD:214581	37/140 (26%)
		SPFH_SLP-1	94..224	CDD:259814	33/125 (26%)
		SCP2	305..396	CDD:280250
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0330
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810