DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Stoml2 and Stoml2

DIOPT Version :9

Sequence 1:	NP_001261161.1	Gene:	Stoml2 / 37807	FlyBaseID:	FBgn0034936	Length:	366	Species:	Drosophila melanogaster
Sequence 2:	NP_075720.1	Gene:	Stoml2 / 66592	MGIID:	1913842	Length:	353	Species:	Mus musculus

Alignment Length:	356	Identity:	212/356 - (59%)
Similarity:	274/356 - (76%)	Gaps:	21/356 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 SLVQQDFLLAGSWIPSQSRRGKASTPINMCVMFVPQQEAWVVERMGRFHRILDPGLNILVPVADK 77
            :|:.:..:.|...:|   ||..:..|.|..::||||||||||||||||||||:||||:|:||.|:
Mouse    11 ALLLRGSVQASGRVP---RRASSGLPRNTVILFVPQQEAWVVERMGRFHRILEPGLNVLIPVLDR 72

  Fly    78 IKYVQSLKEIAIDVPKQSAITSDNVTLSIDGVLYLRIIDPYKASYGVEDPEFAITQLAQTTMRSE 142
            |:||||||||.|:||:|||:|.|||||.|||||||||:|||||||||||||:|:|||||||||||
Mouse    73 IRYVQSLKEIVINVPEQSAVTLDNVTLQIDGVLYLRIMDPYKASYGVEDPEYAVTQLAQTTMRSE 137

  Fly   143 LGKMSMDKVFRERESLNVSIVDSINKASEAWGIACLRYEIRDIRLPTRVHEAMQMQVEAERRKRA 207
            |||:|:|||||||||||.:|||:||:|::.|||.||||||:||.:|.||.|:|||||||||||||
Mouse   138 LGKLSLDKVFRERESLNANIVDAINQAADCWGIRCLRYEIKDIHVPPRVKESMQMQVEAERRKRA 202

  Fly   208 AILESEGVREAEINIAEGKRKSRILASEAERQEHINKASGEAAAIIAVADARARSLLAIAKSLSH 272
            .:|||||.||:.||:||||::::|||||||:.|.||:|:|||:|::|.|.|:|.::..:|.:|:.
Mouse   203 TVLESEGTRESAINVAEGKKQAQILASEAEKAEQINQAAGEASAVLAKAKAKAEAIRILAGALTQ 267

  Fly   273 LDGQNAASLTLAEQYIGAFKKLAKTNNTMILPSNPGDVNGFVAQALAVYNHVS--------NSNQ 329
            .:|..|||||:||||:.||.||||.:||::|||||.||...||||:.||..::        ||:|
Mouse   268 HNGDAAASLTVAEQYVSAFSKLAKDSNTVLLPSNPSDVTSMVAQAMGVYGALTKAPVPGAQNSSQ 332

  Fly   330 ATKSSENVKGVGACLNAKSVEYKELQEDKSS 360
            :.:.          :.|.....:||...|.|
Mouse   333 SRRD----------VQATDTSIEELGRVKLS 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Stoml2	NP_001261161.1	PHB	41..199	CDD:214581	122/157 (78%)
		SPFH_paraslipin	80..188	CDD:259811	86/107 (80%)
		Band_7_C	266..326	CDD:292817	33/67 (49%)
Stoml2	NP_075720.1	HflC	38..314	CDD:223407	193/275 (70%)
		SPFH_paraslipin	74..184	CDD:259811	87/109 (80%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	324..353		5/28 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850727
Domainoid	1	1.000	285	1.000	Domainoid score	I1606
eggNOG	1	0.900	-	-		E1_COG0330
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8389
Inparanoid	1	1.050	416	1.000	Inparanoid score	I1807
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54199
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003634
OrthoInspector	1	1.000	-	-		oto92970
orthoMCL	1	0.900	-	-		OOG6_101622
Panther	1	1.100	-	-	LDO	PTHR43327
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1864
SonicParanoid	1	1.000	-	-		X2984
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790