DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Stoml2 and stoml2

DIOPT Version :9

Sequence 1:	NP_001261161.1	Gene:	Stoml2 / 37807	FlyBaseID:	FBgn0034936	Length:	366	Species:	Drosophila melanogaster
Sequence 2:	NP_001004808.1	Gene:	stoml2 / 448051	XenbaseID:	XB-GENE-1017042	Length:	350	Species:	Xenopus tropicalis

Alignment Length:	321	Identity:	204/321 - (63%)
Similarity:	260/321 - (80%)	Gaps:	7/321 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LLAGS-------WIPSQSRRGKASTPINMCVMFVPQQEAWVVERMGRFHRILDPGLNILVPVADK 77
            ||.||       |.....|...:..|:|..|:|||||||||:||||||||||:||||:|:|:.|:
Frog    12 LLRGSQVHYPRTWNREAQRCLSSGLPMNTVVLFVPQQEAWVIERMGRFHRILEPGLNVLIPILDR 76

  Fly    78 IKYVQSLKEIAIDVPKQSAITSDNVTLSIDGVLYLRIIDPYKASYGVEDPEFAITQLAQTTMRSE 142
            |:||||||||.|:||:|||::.|||||.|||||||||:|||||||||||||:|:|||||||||||
Frog    77 IRYVQSLKEIVINVPEQSAVSLDNVTLQIDGVLYLRIMDPYKASYGVEDPEYAVTQLAQTTMRSE 141

  Fly   143 LGKMSMDKVFRERESLNVSIVDSINKASEAWGIACLRYEIRDIRLPTRVHEAMQMQVEAERRKRA 207
            |||:::|||||||||||.:|||:||:||:.|||.||||||:||.:|.:|.|||||||||||||||
Frog   142 LGKLTLDKVFRERESLNANIVDAINQASDYWGIKCLRYEIKDIHVPPKVKEAMQMQVEAERRKRA 206

  Fly   208 AILESEGVREAEINIAEGKRKSRILASEAERQEHINKASGEAAAIIAVADARARSLLAIAKSLSH 272
            .:|||||.||:.||:|||:::::||||||||.|.||||:|||.||:|.|.||..::..:|::|:.
Frog   207 MVLESEGTRESAINVAEGQKQAQILASEAERAEQINKAAGEANAILAKAKARGDAIRMLAEALTQ 271

  Fly   273 LDGQNAASLTLAEQYIGAFKKLAKTNNTMILPSNPGDVNGFVAQALAVYNHVSNSNQATKS 333
            .:|..|||||:||||:.||.||||.:||::||:|.||::..||||:.:|..::....|..|
Frog   272 QNGNAAASLTVAEQYVLAFSKLAKESNTILLPTNTGDISSMVAQAMGIYGKMTQQQLAQSS 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Stoml2	NP_001261161.1	PHB	41..199	CDD:214581	120/157 (76%)
		SPFH_paraslipin	80..188	CDD:259811	85/107 (79%)
		Band_7_C	266..326	CDD:292817	30/59 (51%)
stoml2	NP_001004808.1	HflC	45..318	CDD:223407	191/272 (70%)
stoml2	NP_001004808.1	SPFH_paraslipin	78..188	CDD:259811	85/109 (78%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	282	1.000	Domainoid score	I1642
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H8389
Inparanoid	1	1.050	410	1.000	Inparanoid score	I1824
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1237942at2759
OrthoFinder	1	1.000	-	-		FOG0003634
OrthoInspector	1	1.000	-	-		oto103232
Panther	1	1.100	-	-	LDO	PTHR43327
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1864
SonicParanoid	1	1.000	-	-		X2984
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	10.190