DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Stoml2 and Stoml2

DIOPT Version :9

Sequence 1:	NP_001261161.1	Gene:	Stoml2 / 37807	FlyBaseID:	FBgn0034936	Length:	366	Species:	Drosophila melanogaster
Sequence 2:	NP_001026816.1	Gene:	Stoml2 / 298203	RGDID:	1308285	Length:	353	Species:	Rattus norvegicus

Alignment Length:	328	Identity:	208/328 - (63%)
Similarity:	267/328 - (81%)	Gaps:	11/328 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 SLVQQDFLLAGSWIPSQSRRGKASTPINMCVMFVPQQEAWVVERMGRFHRILDPGLNILVPVADK 77
            :|:.:..:.|...||   ||..:..|.|..::||||||||||||||||||||:||||:|:||.|:
  Rat    11 ALLLRGSVQASGRIP---RRASSGLPRNTVILFVPQQEAWVVERMGRFHRILEPGLNVLIPVLDR 72

  Fly    78 IKYVQSLKEIAIDVPKQSAITSDNVTLSIDGVLYLRIIDPYKASYGVEDPEFAITQLAQTTMRSE 142
            |:||||||||.|:||:|||:|.|||||.|||||||||:|||||||||||||:|:|||||||||||
  Rat    73 IRYVQSLKEIVINVPEQSAVTLDNVTLQIDGVLYLRIMDPYKASYGVEDPEYAVTQLAQTTMRSE 137

  Fly   143 LGKMSMDKVFRERESLNVSIVDSINKASEAWGIACLRYEIRDIRLPTRVHEAMQMQVEAERRKRA 207
            |||:|:|||||||||||.:|||:||:|::.|||.||||||:||.:|.||.|:|||||||||||||
  Rat   138 LGKLSLDKVFRERESLNANIVDAINQAADCWGIRCLRYEIKDIHVPPRVKESMQMQVEAERRKRA 202

  Fly   208 AILESEGVREAEINIAEGKRKSRILASEAERQEHINKASGEAAAIIAVADARARSLLAIAKSLSH 272
            .:|||||.||:.||:||||::::|||||||:.|.||:|:|||:|::|.|.|:|.::..:|.:|:.
  Rat   203 TVLESEGTRESAINVAEGKKQAQILASEAEKAEQINQAAGEASAVLAKAKAKAEAIRILAGALTQ 267

  Fly   273 LDGQNAASLTLAEQYIGAFKKLAKTNNTMILPSNPGDVNGFVAQALAVYNHVS--------NSNQ 329
            .:|..|||||:||||:.||.||||.:||::|||||.||...||||:.||..::        ||::
  Rat   268 HNGDAAASLTVAEQYVSAFSKLAKDSNTVLLPSNPSDVTSMVAQAMGVYGALTKAPVPGAQNSSE 332

  Fly   330 ATK 332
            |.:
  Rat   333 ARR 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Stoml2	NP_001261161.1	PHB	41..199	CDD:214581	122/157 (78%)
		SPFH_paraslipin	80..188	CDD:259811	86/107 (80%)
		Band_7_C	266..326	CDD:292817	33/67 (49%)
Stoml2	NP_001026816.1	HflC	38..314	CDD:223407	193/275 (70%)
		SPFH_paraslipin	74..184	CDD:259811	87/109 (80%)
		Band_7_C	259..321	CDD:292817	33/61 (54%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	324..353		3/7 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166354432
Domainoid	1	1.000	285	1.000	Domainoid score	I1550
eggNOG	1	0.900	-	-		E1_COG0330
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8389
Inparanoid	1	1.050	415	1.000	Inparanoid score	I1775
OMA	1	1.010	-	-		QHG54199
OrthoDB	1	1.010	-	-		D1237942at2759
OrthoFinder	1	1.000	-	-		FOG0003634
OrthoInspector	1	1.000	-	-		oto96524
orthoMCL	1	0.900	-	-		OOG6_101622
Panther	1	1.100	-	-	LDO	PTHR43327
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2984
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770