DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Stoml2 and stl-1

DIOPT Version :9

Sequence 1:	NP_001261161.1	Gene:	Stoml2 / 37807	FlyBaseID:	FBgn0034936	Length:	366	Species:	Drosophila melanogaster
Sequence 2:	NP_001251105.1	Gene:	stl-1 / 172777	WormBaseID:	WBGene00006061	Length:	324	Species:	Caenorhabditis elegans

Alignment Length:	319	Identity:	195/319 - (61%)
Similarity:	252/319 - (78%)	Gaps:	5/319 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LVQQDFLLAGSWIP---SQSRRGKASTPINMCVMFVPQQEAWVVERMGRFHRILDPGLNILVPVA 75
            |:....||..|.:|   :.||:..|:.  |..:.||||||||||||||:|::||:||||.|:|:.
Worm     8 LMNSSALLRSSTLPLAVTSSRQAHAAH--NTVINFVPQQEAWVVERMGKFYKILEPGLNFLLPII 70

  Fly    76 DKIKYVQSLKEIAIDVPKQSAITSDNVTLSIDGVLYLRIIDPYKASYGVEDPEFAITQLAQTTMR 140
            ||||:||:|:||||::|:|.|||.|||.|.:|||||||:.|||||||||:|||||:|||||||||
Worm    71 DKIKFVQNLREIAIEIPEQGAITIDNVQLRLDGVLYLRVFDPYKASYGVDDPEFAVTQLAQTTMR 135

  Fly   141 SELGKMSMDKVFRERESLNVSIVDSINKASEAWGIACLRYEIRDIRLPTRVHEAMQMQVEAERRK 205
            ||:||:::|.||:|||.||.:||.:|||||..|||.|:||||||:::|:::.|||||||||||:|
Worm   136 SEVGKINLDTVFKERELLNENIVFAINKASAPWGIQCMRYEIRDMQMPSKIQEAMQMQVEAERKK 200

  Fly   206 RAAILESEGVREAEINIAEGKRKSRILASEAERQEHINKASGEAAAIIAVADARARSLLAIAKSL 270
            |||||||||:|||.||.|||.:||.||||||.:.|.||.|.|||.|:|..|::||:::..||.:|
Worm   201 RAAILESEGIREAAINRAEGDKKSAILASEAVQAERINVAKGEAEAVILKAESRAKAIERIALAL 265

  Fly   271 SHLDGQNAASLTLAEQYIGAFKKLAKTNNTMILPSNPGDVNGFVAQALAVYNHVSNSNQ 329
            ....|.|||.||:||||:|||..|||.:||::||:|..|....|:||||||:.:||..:
Worm   266 EKDGGANAAGLTVAEQYVGAFGNLAKESNTVVLPANLSDPGSMVSQALAVYDSLSNKKK 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Stoml2	NP_001261161.1	PHB	41..199	CDD:214581	108/157 (69%)
		SPFH_paraslipin	80..188	CDD:259811	75/107 (70%)
		Band_7_C	266..326	CDD:292817	32/59 (54%)
stl-1	NP_001251105.1	HflC	41..298	CDD:223407	172/256 (67%)
stl-1	NP_001251105.1	SPFH_paraslipin	75..184	CDD:259811	75/108 (69%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167804
Domainoid	1	1.000	262	1.000	Domainoid score	I1035
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8389
Inparanoid	1	1.050	380	1.000	Inparanoid score	I1191
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54199
OrthoDB	1	1.010	-	-		D1237942at2759
OrthoFinder	1	1.000	-	-		FOG0003634
OrthoInspector	1	1.000	-	-		oto17793
orthoMCL	1	0.900	-	-		OOG6_101622
Panther	1	1.100	-	-	LDO	PTHR43327
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1864
SonicParanoid	1	1.000	-	-		X2984
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.940