DRSC/TRiP Functional Genomics Resources

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Protein Alignment Galphas and Gna15

DIOPT Version :9

Sequence 1:NP_001163283.1 Gene:Galphas / 37805 FlyBaseID:FBgn0001123 Length:385 Species:Drosophila melanogaster
Sequence 2:NP_445994.2 Gene:Gna15 / 89788 RGDID:619751 Length:374 Species:Rattus norvegicus


Alignment Length:379 Identity:134/379 - (35%)
Similarity:200/379 - (52%) Gaps:28/379 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly    16 SEDSKSQKRRSDAISRQLQKDKQLYRATHRLLLLGAGESGKSTIVKQMRILHVDGFSDSEKKQKI 80
            :|:.|:..|....|::.|.:.|:..|...:|||||.|||||||.:|||||:|..|:|:.:::...
  Rat    15 TEEEKTAARIDQEINKILLEQKKQERGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEDRRAFR 79

  Fly    81 DDIKKNIRDAILTITGAMSTLNPPVALEKKENEPRVEYIQDYASSPDFNYPPEFYEHTEELWKDK 145
            ..:.:||..::..:..||..|..|.:....:....:...||......|..|  :....:.||:|.
  Rat    80 LLVYQNIFVSMQAMIEAMDRLQIPFSRPDSKQHASLVMTQDPYKVSSFEKP--YAVAMQYLWRDA 142

  Fly   146 GVLQTYERSNEYQLIDCAKYFLDRVSTIKNPNYTPNEQDILRCRVLTSGIFETRFQVDKVNFHMF 210
            |:...|||..|:.|:|.|.|:|..:..|...:|.|..||:||.|:.|:||.|..|.|.|....:.
  Rat   143 GIRACYERRREFHLLDSAVYYLSHLERIAEDDYIPTAQDVLRSRMPTTGINEYCFSVQKTKLRIV 207

  Fly   211 DVGGQRDERRKWIQCFNDVTAIIFVTACSSYNMVLREDPTQNRLRESLDLFKSIWNNRWLRTISI 275
            |||||:.||:|||.||.:|.|:|::.:.|.|:..|.|:..:||::|||.||.:|....|.::.|:
  Rat   208 DVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENSQENRMKESLALFSTILELPWFKSTSV 272

  Fly   276 ILFLNKQDLLAEKIKAGKSKLSEYFSEFNKYQTPIDTGDAIMESNDDPEVIRAKYFIRDEFLRIS 340
            ||||||.|:|.:||..  |.|:.||..|   |.|....:|            ||.||.|.:.|:.
  Rat   273 ILFLNKTDILEDKIHT--SHLASYFPSF---QGPRRDAEA------------AKRFILDMYARVY 320

  Fly   341 TA---------SGDGKHYCYPHFTCAVDTENIKRVFNDCRDIIQRMHLRQYELL 385
            .:         .|......:.|||||.||.:::.||.|.||.:...:|.:..||
  Rat   321 ASCAEPHDGGRKGSRARRLFAHFTCATDTHSVRSVFKDVRDSVLARYLDEINLL 374

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GalphasNP_001163283.1 G-alpha 44..379 CDD:206639 124/343 (36%)
Gna15NP_445994.2 G-alpha 43..368 CDD:206639 124/343 (36%)
G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230 44..57 10/12 (83%)
G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230 181..189 4/7 (57%)
G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230 273..280 6/6 (100%)
G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230 344..349 3/4 (75%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0082
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D754573at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
43.820

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