Protein Alignment Galphas and Gna12

DIOPT Version :9

• Sequence 1: NP_001163283.1
• Gene: Galphas / 37805
• FlyBaseID: FBgn0001123
• Length: 385
• Species: Drosophila melanogaster
• Sequence 2: NP_112296.1
• Gene: Gna12 / 81663
• RGDID: 71018
• Length: 379
• Species: Rattus norvegicus
• Alignment Length: 369
• Identity: 135/369 - (36%)
• Similarity: 199/369 - (53%)
• Gaps: 26/369 - (7%)

  Fly    20 KSQKRRSDAISRQLQKDKQLYRATHRLLLLGAGESGKSTIVKQMRILHVDGFSDSEKKQKIDDIK 84
            :..:|||..|...|.::::..|...::||||||||||||.:|||||:|...|......:..|.|.
  Rat    32 REARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIF 96

  Fly    85 KNIRDAILTITGAMSTLNPPVALEKKENEPRVEYIQDYASSPDFNYPPEFYE----HTEELWKDK 145
            .||......:..|...|..|  .:..|||....::..:.:.......|..::    ....||:|.
  Rat    97 DNILKGSRVLVDARDKLGIP--WQHSENEKHGMFLMAFENKAGLPVEPATFQLYVPALSALWRDS 159

  Fly   146 GVLQTYERSNEYQLIDCAKYFLDRVSTIKNPNYTPNEQDILRCRVLTSGIFETRFQVDKVNFHMF 210
            |:.:.:.|.:|:||.:..|||||.:..|...||.|::||||..|..|.||.|..|.:.|:.|.|.
  Rat   160 GIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMV 224

  Fly   211 DVGGQRDERRKWIQCFNDVTAIIFVTACSSYNMVLREDPTQNRLRESLDLFKSIWNNRWLRTISI 275
            ||||||.:|:||.|||:.:|:|:|:.:.|.|:.||.||...|||.||:::|::|.||:....:||
  Rat   225 DVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSI 289

  Fly   276 ILFLNKQDLLAEKIKAGKSKLSEYFSEFNKYQTPIDTGDAIMESNDDPEVIRAKYFIRDEFLRIS 340
            ||||||.|||.||:|:  ..:.::|.:|.        ||.  ...:|.:....:.|.|....|
  Rat   290 ILFLNKMDLLVEKVKS--VSIKKHFPDFK--------GDP--HRLEDVQRYLVQCFDRKRRNR-- 340

  Fly   341 TASGDGKHYCYPHFTCAVDTENIKRVFNDCRDIIQRMHLRQYEL 384
                 ||. .:.|||.|:|||||:.||:..:|.|.:.:|:...|
  Rat   341 -----GKP-LFHHFTTAIDTENIRFVFHAVKDTILQENLKDIML 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphas	NP_001163283.1	G-alpha	44..379	CDD:206639	127/338 (38%)
Gna12	NP_112296.1	G_alpha	40..377	CDD:214595	131/358 (37%)
		G-alpha	56..373	CDD:206639	127/338 (38%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	57..70		10/12 (83%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	198..206		4/7 (57%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	221..230		6/8 (75%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	290..297		6/6 (100%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	349..354		2/4 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910