DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Galphas and gnaq

DIOPT Version :9

Sequence 1:	NP_001163283.1	Gene:	Galphas / 37805	FlyBaseID:	FBgn0001123	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_001037982.1	Gene:	gnaq / 733773	XenbaseID:	XB-GENE-973433	Length:	359	Species:	Xenopus tropicalis

Alignment Length:	372	Identity:	152/372 - (40%)
Similarity:	213/372 - (57%)	Gaps:	26/372 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 SEDSKSQKRRSDAISRQLQKDKQLYRATHRLLLLGAGESGKSTIVKQMRILHVDGFSDSEKKQKI 80
            ||::|..:|.:|.|.|||::||:..|...:|||||.|||||||.:|||||:|..|:||.:|:...
Frog    12 SEEAKEARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDKRGFT 76

  Fly    81 DDIKKNIRDAILTITGAMSTLNPPVALEKKENEPRVEYIQDYASSPDFNYPPEFYEHTEELWKDK 145
            ..:.:||..|:..:..||.||..|...|..:....:....|......|..|  :.:..:.||.|.
Frog    77 KLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKGHALLIREVDVEKVASFENP--YVDAIKYLWNDP 139

  Fly   146 GVLQTYERSNEYQLIDCAKYFLDRVSTIKNPNYTPNEQDILRCRVLTSGIFETRFQVDKVNFHMF 210
            |:.:.|:|..||||.|..||:|:.:..|.:..|.|::||:||.||.|:||.|..|.:..|.|.|.
Frog   140 GIQEAYDRRREYQLSDSTKYYLNDLDRIASQGYLPSQQDVLRVRVPTTGIIEYPFDLQSVIFRMV 204

  Fly   211 DVGGQRDERRKWIQCFNDVTAIIFVTACSSYNMVLREDPTQNRLRESLDLFKSIWNNRWLRTISI 275
            ||||||.||||||.||.:||:|:|:.|.|.|:.||.|...:||:.||..||::|....|.:..|:
Frog   205 DVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSV 269

  Fly   276 ILFLNKQDLLAEKIKAGKSKLSEYFSEFNKYQTPIDTGDAIMESNDDP--EVIRAKYFIRDEFLR 338
            ||||||:|||.|||.  .|.|.:||.|:                 |.|  :...|:.||...|:.
Frog   270 ILFLNKKDLLEEKIM--YSHLVDYFPEY-----------------DGPQRDAQAAREFILKMFVD 315

  Fly   339 ISTASGDGKHYCYPHFTCAVDTENIKRVFNDCRDIIQRMHLRQYELL 385
            ::.   |.....|.|||||.|||||:.||...:|.|.:::|::|.|:
Frog   316 LNP---DSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Galphas	NP_001163283.1	G-alpha	44..379	CDD:206639	137/336 (41%)
gnaq	NP_001037982.1	G-alpha	40..353	CDD:206639	137/336 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920