DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Galphas and gnaq

DIOPT Version :9

Sequence 1:	NP_001163283.1	Gene:	Galphas / 37805	FlyBaseID:	FBgn0001123	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_001138271.1	Gene:	gnaq / 570108	ZFINID:	ZDB-GENE-081104-25	Length:	359	Species:	Danio rerio

Alignment Length:	370	Identity:	149/370 - (40%)
Similarity:	217/370 - (58%)	Gaps:	22/370 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 SEDSKSQKRRSDAISRQLQKDKQLYRATHRLLLLGAGESGKSTIVKQMRILHVDGFSDSEKKQKI 80
            ||::|..:|.:|.|.|||::||:..|...:|||||.|||||||.:|||||:|..|:|:.::|...
Zfish    12 SEEAKEARRINDEIDRQLRRDKKDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSEEDRKGFT 76

  Fly    81 DDIKKNIRDAILTITGAMSTLNPPVALEKKENEPRVEYIQDYASSPDFNYPPEFYEHTEELWKDK 145
            ..:.:||..:..::..||.||.  :..:.:.|:.....:::......|.:...:.:..:.||.|.
Zfish    77 KLVYQNIFTSSQSMIRAMDTLQ--ILYKYEHNKANANIVREVDVEKVFLFVNPYVDAIKSLWNDP 139

  Fly   146 GVLQTYERSNEYQLIDCAKYFLDRVSTIKNPNYTPNEQDILRCRVLTSGIFETRFQVDKVNFHMF 210
            |:.:.|:|..||||.|..||:|:.:..|.||:|.|.:||:||.||.|:||.|..|.:..|.|.|.
Zfish   140 GIQECYDRRREYQLSDSTKYYLNSLDRIANPSYIPTQQDVLRVRVPTTGIIEYPFDLQSVIFRMV 204

  Fly   211 DVGGQRDERRKWIQCFNDVTAIIFVTACSSYNMVLREDPTQNRLRESLDLFKSIWNNRWLRTISI 275
            ||||||.||||||.||.:||:|:|:.|.|.|:.||.|...:||:.||..||::|....|.:..|:
Zfish   205 DVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSV 269

  Fly   276 ILFLNKQDLLAEKIKAGKSKLSEYFSEFNKYQTPIDTGDAIMESNDDPEVIRAKYFIRDEFLRIS 340
            ||||||:|||.|||..  |.|.:||.|::..|....|               |:.||...|:.::
Zfish   270 ILFLNKKDLLEEKIMF--SHLVDYFPEYDGPQRDAQT---------------AREFILKMFVDLN 317

  Fly   341 TASGDGKHYCYPHFTCAVDTENIKRVFNDCRDIIQRMHLRQYELL 385
            .   |.:...|.|||||.|||||:.||...:|.|.::.|::|.|:
Zfish   318 P---DSEKIIYSHFTCATDTENIRFVFAAVKDTILQLTLKEYNLV 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Galphas	NP_001163283.1	G-alpha	44..379	CDD:206639	134/334 (40%)
gnaq	NP_001138271.1	G_alpha	19..357	CDD:214595	144/359 (40%)
gnaq	NP_001138271.1	G-alpha	40..353	CDD:206639	134/334 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820