Protein Alignment Galphas and gnas

DIOPT Version :9

• Sequence 1: NP_001163283.1
• Gene: Galphas / 37805
• FlyBaseID: FBgn0001123
• Length: 385
• Species: Drosophila melanogaster
• Sequence 2: XP_001335732.1
• Gene: gnas / 557353
• ZFINID: ZDB-GENE-090417-2
• Length: 419
• Species: Danio rerio
• Alignment Length: 366
• Identity: 268/366 - (73%)
• Similarity: 308/366 - (84%)
• Gaps: 3/366 - (0%)

  Fly    20 KSQKRRSDAISRQLQKDKQLYRATHRLLLLGAGESGKSTIVKQMRILHVDGFSDSEKKQKIDDIK 84
            |::.:||..|.:.|:.:|:.|:.||||||||||||||||||||||||||:||:..||||||.|||
Zfish    57 KAENKRSRNIDKSLKAEKREYKQTHRLLLLGAGESGKSTIVKQMRILHVNGFNAEEKKQKIQDIK 121

  Fly    85 KNIRDAILTITGAMSTLNPPVALEKKENEPRVEYIQDYASSPDFNYPPEFYEHTEELWKDKGVLQ 149
            .||::||.||..|||.|.|||.|....|:.|::||.:.|:..||.:..||||||:.||:|:||..
Zfish   122 NNIKEAIETIVTAMSVLVPPVQLACPANKFRIDYILNLANQKDFEFTTEFYEHTKTLWQDEGVKA 186

  Fly   150 TYERSNEYQLIDCAKYFLDRVSTIKNPNYTPNEQDILRCRVLTSGIFETRFQVDKVNFHMFDVGG 214
            .:||||||||||||:|||||:.|:|..:|||.:||:|||||||||||||||||||||||||||||
Zfish   187 CFERSNEYQLIDCAQYFLDRIDTVKQSDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGG 251

  Fly   215 QRDERRKWIQCFNDVTAIIFVTACSSYNMVLREDPTQNRLRESLDLFKSIWNNRWLRTISIILFL 279
            |||||||||||||||||||||.|.||||||||||...|||:|:|:|||:|||||||||||:||||
Zfish   252 QRDERRKWIQCFNDVTAIIFVVASSSYNMVLREDNQTNRLQEALNLFKNIWNNRWLRTISVILFL 316

  Fly   280 NKQDLLAEKIKAGKSKLSEYFSEFNKYQTPIDTGDAIMESNDDPEVIRAKYFIRDEFLRISTASG 344
            |||||||||:.|||||:.:||.||.:|.||   .||..|..:||.|.||||||||||||||||||
Zfish   317 NKQDLLAEKVLAGKSKIEDYFPEFARYTTP---DDATPEQGEDPRVTRAKYFIRDEFLRISTASG 378

  Fly   345 DGKHYCYPHFTCAVDTENIKRVFNDCRDIIQRMHLRQYELL 385
            ||:||||||||||||||||:|||||||||||||||||||||
Zfish   379 DGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphas	NP_001163283.1	G-alpha	44..379	CDD:206639	252/334 (75%)
gnas	XP_001335732.1	G_alpha	61..416	CDD:214595	262/357 (73%)
		G-alpha	81..413	CDD:206639	252/334 (75%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	537	1.000	Domainoid score	I264
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55534
Inparanoid	1	1.050	572	1.000	Inparanoid score	I1021
OMA	1	1.010	-	-		QHG48884
OrthoDB	1	1.010	-	-		D325067at33208
OrthoFinder	1	1.000	-	-		FOG0004018
OrthoInspector	1	1.000	-	-		otm26292
orthoMCL	1	0.900	-	-		OOG6_106085
Panther	1	1.100	-	-	LDO	PTHR10218
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3262
SonicParanoid	1	1.000	-	-		X2771
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.970