DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Galphas and gna14a

DIOPT Version :9

Sequence 1:	NP_001163283.1	Gene:	Galphas / 37805	FlyBaseID:	FBgn0001123	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	XP_683989.2	Gene:	gna14a / 556160	ZFINID:	ZDB-GENE-081105-76	Length:	354	Species:	Danio rerio

Alignment Length:	371	Identity:	155/371 - (41%)
Similarity:	212/371 - (57%)	Gaps:	24/371 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 SEDSKSQKRRSDAISRQLQKDKQLYRATHRLLLLGAGESGKSTIVKQMRILHVDGFSDSEKKQKI 80
            |.:.|.::|.:..|.:||:|||:..|...:|||||.|||||||.:|||||:|..|::|.:||..|
Zfish     7 SAEEKERQRINQEIDKQLRKDKKDSRRELKLLLLGTGESGKSTFIKQMRIIHGSGYTDDDKKGFI 71

  Fly    81 DDIKKNIRDAILTITGAMSTLNPPVALEKKENEPRVEYIQDYASSPDFNYPPEFYEHTEELWKDK 145
            ..:.:|...|:.::..||..|.  :|....||:.....:.|.......:......:....||.|.
Zfish    72 KLVHQNTLSAMQSMVRAMDMLK--IAYANSENQAHSALVNDIEVDKIMSLDETQVKALSSLWSDS 134

  Fly   146 GVLQTYERSNEYQLIDCAKYFLDRVSTIKNPNYTPNEQDILRCRVLTSGIFETRFQVDKVNFHMF 210
            |:.:.|:|..||||.|.|||:|..:..|.|..|.|.||||||.||.|:||.|..|.:|.|.|.|.
Zfish   135 GIQECYDRRREYQLTDSAKYYLSDLDRIANAAYVPTEQDILRVRVPTTGIIEYPFDLDNVIFRMV 199

  Fly   211 DVGGQRDERRKWIQCFNDVTAIIFVTACSSYNMVLREDPTQNRLRESLDLFKSIWNNRWLRTISI 275
            ||||||.||||||.||.:||:|||:.|.|.|:.||.|...:||:.||..|||:|....|.::.|:
Zfish   200 DVGGQRSERRKWIHCFENVTSIIFLVALSEYDQVLAECDNENRMEESKALFKTIITYPWFQSSSV 264

  Fly   276 ILFLNKQDLLAEKIKAGKSKLSEYFSEFNKYQTPIDTGDAIMESNDDPEVIRAKYFIRDEFLRIS 340
            ||||||.|:|.|||.  .|.::.||.||        ||     ..:||:.  |:.||    |::.
Zfish   265 ILFLNKTDILKEKIV--YSHVATYFPEF--------TG-----PKNDPKA--AQEFI----LKMY 308

  Fly   341 TASGDGK-HYCYPHFTCAVDTENIKRVFNDCRDIIQRMHLRQYELL 385
            ....:.| ...|.|||||.|||||:.:|...:|.|.|.:|:::.|:
Zfish   309 QEENEDKDKTIYSHFTCATDTENIRLIFAAVKDTILRHNLKEFNLV 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Galphas	NP_001163283.1	G-alpha	44..379	CDD:206639	143/335 (43%)
gna14a	XP_683989.2	G_alpha	15..352	CDD:214595	152/359 (42%)
gna14a	XP_683989.2	G-alpha	35..348	CDD:206639	143/335 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920