DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Galphas and Gnat1

DIOPT Version :9

Sequence 1:	NP_001163283.1	Gene:	Galphas / 37805	FlyBaseID:	FBgn0001123	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_001102250.2	Gene:	Gnat1 / 363143	RGDID:	1304683	Length:	350	Species:	Rattus norvegicus

Alignment Length:	363	Identity:	154/363 - (42%)
Similarity:	222/363 - (61%)	Gaps:	23/363 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 SKSQKRRSDAISRQLQKDKQLYRATHRLLLLGAGESGKSTIVKQMRILHVDGFSDSEKKQKIDDI 83
            :.::::.|..:.::|::|.:....|.:||||||||||||||||||:|:|.||:|..|..:.|..|
  Rat     5 ASAEEKHSRELEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDGYSLEECLEFIAII 69

  Fly    84 KKNIRDAILTITGAMSTLNPPVALEKKENEPR-VEYIQDYASSPDFNYPPEFYEHTEELWKDKGV 147
            ..|...:||.|..||:|||.......::::.| :.::.|  :..:...|.|..:..:.||||.|:
  Rat    70 YGNTLQSILAIVRAMTTLNIQYGDSARQDDARKLMHMAD--TIEEGTMPKEMSDIIQRLWKDSGI 132

  Fly   148 LQTYERSNEYQLIDCAKYFLDRVSTIKNPNYTPNEQDILRCRVLTSGIFETRFQVDKVNFHMFDV 212
            ...::|::||||.|.|.|:|..:..:..|.|.|.|||:||.||.|:||.||:|....:||.||||
  Rat   133 QACFDRASEYQLNDSAGYYLSDLERLVTPGYVPTEQDVLRSRVKTTGIIETQFSFKDLNFRMFDV 197

  Fly   213 GGQRDERRKWIQCFNDVTAIIFVTACSSYNMVLREDPTQNRLRESLDLFKSIWNNRWLRTISIIL 277
            ||||.||:|||.||..||.|||:.|.|:|:|||.||...||:.|||.||.||.|:|:..|.||:|
  Rat   198 GGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDDEVNRMHESLHLFNSICNHRYFATTSIVL 262

  Fly   278 FLNKQDLLAEKIKAGKSKLSEYFSEFNKYQTPIDTGDAIMESNDDPEVIRAKYFIRDEFLRISTA 342
            ||||:|:.:||||  |:.||..|.:::...|..|.|:                :|:.:||.::..
  Rat   263 FLNKKDVFSEKIK--KAHLSICFPDYDGPNTYDDAGN----------------YIKVQFLELNMR 309

  Fly   343 SGDGKHYCYPHFTCAVDTENIKRVFNDCRDIIQRMHLR 380
            . |.|. .|.|.|||.||:|:|.||:...|||.:.:|:
  Rat   310 R-DVKE-IYSHMTCATDTQNVKFVFDAVTDIIIKENLK 345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Galphas	NP_001163283.1	G-alpha	44..379	CDD:206639	149/335 (44%)
Gnat1	NP_001102250.2	G-alpha	30..344	CDD:206639	149/335 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820