Protein Alignment Galphas and Gnat3

DIOPT Version :10

• Sequence 1: NP_477505.1
• Gene: Galphas / 37805
• FlyBaseID: FBgn0001123
• Length: 385
• Species: Drosophila melanogaster
• Sequence 2: NP_775162.1
• Gene: Gnat3 / 286924
• RGDID: 727817
• Length: 354
• Species: Rattus norvegicus
• Alignment Length: 371
• Identity: 156/371 - (42%)
• Similarity: 219/371 - (59%)
• Gaps: 33/371 - (8%)

  Fly    16 SEDSKSQKRRSDAISRQLQKDKQLYRATHRLLLLGAGESGKSTIVKQMRILHVDGFSDSEKKQKI 80
            |.:||...:||..:.::||:|.:....|.:||||||||||||||||||:|:|.:|:|..|..:..
  Rat     6 SSESKESAKRSKELEKKLQEDAERDARTVKLLLLGAGESGKSTIVKQMKIIHKNGYSKQECMEFK 70

  Fly    81 DDIKKNIRDAILTITGAMSTL-----NPPVALEKKENEPRVEYIQDYASS-PDFNYPPEFYEHTE 139
            ..:..|...:||.|..||:||     ||    ..:|::   :.:...|:: .|.:..|:..|..:
  Rat    71 AVVYSNTLQSILAIVKAMTTLGIDYVNP----RSREDQ---QLLLSMANTLEDGDMTPQLAEIIK 128

  Fly   140 ELWKDKGVLQTYERSNEYQLIDCAKYFLDRVSTIKNPNYTPNEQDILRCRVLTSGIFETRFQVDK 204
            .||.|.|:...:||::||||.|.|.|:|:.:..:..|.|.|||||:|..||.|:||.||:|....
  Rat   129 RLWGDPGIQACFERASEYQLNDSAAYYLNDLDRLTAPGYVPNEQDVLHSRVKTTGIIETQFSFKD 193

  Fly   205 VNFHMFDVGGQRDERRKWIQCFNDVTAIIFVTACSSYNMVLREDPTQNRLRESLDLFKSIWNNRW 269
            :||.||||||||.||:|||.||..||.|||..|.|:|:|||.||...||:.|||.||.||.|:::
  Rat   194 LNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDEEVNRMHESLHLFNSICNHKY 258

  Fly   270 LRTISIILFLNKQDLLAEKIKAGKSKLSEYFSEFNKYQTPIDTGDAIMESNDDPEVIRAKYFIRD 334
            ..|.||:|||||:||..||:.  |..||..|.|:....|..|.|:                :|::
  Rat   259 FATTSIVLFLNKKDLFQEKVT--KVHLSICFPEYTGPNTFEDAGN----------------YIKN 305

  Fly   335 EFLRISTASGDGKHYCYPHFTCAVDTENIKRVFNDCRDIIQRMHLR 380
            :||.::....|.:  .|.|.|||.||:|:|.||:...|||.:.:|:
  Rat   306 QFLDLNLKKEDKE--IYSHMTCATDTQNVKFVFDAVTDIIIKENLK 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphas	NP_477505.1	G-alpha	44..379	CDD:206639	146/340 (43%)
Gnat3	NP_775162.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..27		7/20 (35%)
		G-alpha	34..348	CDD:206639	146/340 (43%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	35..48		11/12 (92%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	173..181		4/7 (57%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	196..205		7/8 (88%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	265..272		5/6 (83%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	324..329		3/4 (75%)