Protein Alignment Galphas and Gnaz

DIOPT Version :10

• Sequence 1: NP_477505.1
• Gene: Galphas / 37805
• FlyBaseID: FBgn0001123
• Length: 385
• Species: Drosophila melanogaster
• Sequence 2: NP_037321.1
• Gene: Gnaz / 25740
• RGDID: 2717
• Length: 355
• Species: Rattus norvegicus
• Alignment Length: 392
• Identity: 149/392 - (38%)
• Similarity: 203/392 - (51%)
• Gaps: 54/392 - (13%)

  Fly     1 MGCFGSPTSKQSDVNSEDSKSQKRRSDAISRQLQKDKQLYRATHRLLLLGAGESGKSTIVKQMRI 65
            |||      :|    |.:.|...|||..|.|.|:.:.|..|...:|||||...||||||||||:|
  Rat     1 MGC------RQ----SSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKI 55

  Fly    66 LHVDGFSDSEKKQKIDDIKKNIRDAILTITGAMSTL-----NPPVALEKKENEPRVEYIQDYA-- 123
            :|..||:....|:....|..|..|::..|..|::.|     ||..|.:.         :|.:|
  Rat    56 IHSGGFNLEACKEYKPLIIYNAIDSLTRIIRALAALKIDFHNPDRAYDA---------VQLFALT 111

  Fly   124 --SSPDFNYPPEFYEHTEELWKDKGVLQTYERSNEYQLIDCAKYFLDRVSTIKNPNYTPNEQDIL 186
              :.......||.......||.|.|....:.||:||.|.|.|.|:|:.:..|..|:|.|..:|||
  Rat   112 GPAESKGEITPELLGVMRRLWADPGAQACFGRSSEYHLEDNAAYYLNDLERIAAPDYIPTVEDIL 176

  Fly   187 RCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVTACSSYNMVLREDPTQ 251
            |.|.:|:||.|.:|...::.|.|.||||||.||:|||.||..||||||....|.|::.|.||...
  Rat   177 RSRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQT 241

  Fly   252 NRLRESLDLFKSIWNNRWLRTISIILFLNKQDLLAEKIKAGKSKLSEYFSEF---NKYQTPIDTG 313
            :|:.|||.||.||.||.|....|:||||||:|||:|||:  :..||..|.|:   |.|:
  Rat   242 SRMAESLRLFDSICNNNWFINTSLILFLNKKDLLSEKIR--RIPLSVCFPEYKGQNTYE------ 298

  Fly   314 DAIMESNDDPEVIRAKYFIRDEFLRISTASGDGKHYCYPHFTCAVDTENIKRVFNDCRDIIQRMH 378
                         .|..:|:.:|..:: .:.:.|. .|.|||||.||.||:.||:...|:|.:.:
  Rat   299 -------------EAAVYIQRQFEDLN-RNKETKE-IYSHFTCATDTSNIQFVFDAVTDVIIQNN 348

  Fly   379 LR 380
            |:
  Rat   349 LK 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphas	NP_477505.1	G-alpha	44..379	CDD:206639	134/346 (39%)
Gnaz	NP_037321.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..26		12/34 (35%)
		G-alpha	34..349	CDD:206639	134/346 (39%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	35..48		8/12 (67%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	174..182		5/7 (71%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	197..206		6/8 (75%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	266..273		6/6 (100%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	325..330		3/4 (75%)