DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Galphas and gpa-3

DIOPT Version :9

Sequence 1:	NP_001163283.1	Gene:	Galphas / 37805	FlyBaseID:	FBgn0001123	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_001309498.1	Gene:	gpa-3 / 179319	WormBaseID:	WBGene00001665	Length:	353	Species:	Caenorhabditis elegans

Alignment Length:	375	Identity:	140/375 - (37%)
Similarity:	201/375 - (53%)	Gaps:	41/375 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 SEDSKSQKRRSDAISRQLQKDKQLYRATHRLLLLGAGESGKSTIVKQMRILHVDGFSDSEKKQKI 80
            |.:.|....:|.||.:::.::....:...:||||||||.||||::|||||||..||:..|.:|:.
Worm     6 SAEDKELTLKSKAIDKEMMQNHMSQQKVVKLLLLGAGECGKSTVLKQMRILHDHGFTAEEAEQQK 70

  Fly    81 DDIKKNIRDAILTITGAMSTLNPPVALEKKENEPRV-----EYIQDYASSPDFNYPPEFYEHTEE 140
            ..:..|...|:..|...|..|........:||:.:.     :.:|:...     :|.|.....:.
Worm    71 SVVFNNTLQAMTAILKGMEALRMTFDKPIRENDAKFVMESHKMLQEAKV-----FPEELANAIQA 130

  Fly   141 LWKDKGVLQTYERSNEYQLIDCAKYFLDRVSTIKNPNYTPNEQDILRCRVLTSGIFETRFQVDKV 205
            ||.||.|.|...:.||:|:.:.|.:||..:..||.|:|.|.|||||..|:.|:||.|.:||:..|
Worm   131 LWNDKAVQQVIAKGNEFQMPESAPHFLSSLDRIKLPDYNPTEQDILLSRIKTTGIVEVKFQMKSV 195

  Fly   206 NFHMFDVGGQRDERRKWIQCFNDVTAIIFVTACSSYNMVLREDPTQNRLRESLDLFKSIWNNRWL 270
            :|.:|||||||.||:|||.||.||.||||:.|.|.|:.||.||.|.||:.||:.||:||.|:||.
Worm   196 DFRVFDVGGQRSERKKWIHCFEDVNAIIFIAAISEYDQVLFEDETTNRMIESMRLFESICNSRWF 260

  Fly   271 RTISIILFLNKQDLLAEKIKAGKSKLSEYFSEFNKYQTPIDTGDAIMESNDDPEVIRAKYFIRDE 335
            ...|:||||||:||.|||||  ::.:...|.::...||                        .||
Worm   261 INTSMILFLNKKDLFAEKIK--RTSIKSAFPDYKGAQT------------------------YDE 299

  Fly   336 FLRISTASGDG-----KHYCYPHFTCAVDTENIKRVFNDCRDIIQRMHLR 380
            ..|......||     :...|.|.|||.||:.::.:.:...|:|.:.:|:
Worm   300 SCRYIEEKFDGLNANPEKTIYMHQTCATDTDQVQMILDSVIDMIIQANLQ 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Galphas	NP_001163283.1	G-alpha	44..379	CDD:206639	134/344 (39%)
gpa-3	NP_001309498.1	G-alpha	34..348	CDD:206639	134/344 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162157
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.750