Protein Alignment Galphas and Gnal

DIOPT Version :9

• Sequence 1: NP_001163283.1
• Gene: Galphas / 37805
• FlyBaseID: FBgn0001123
• Length: 385
• Species: Drosophila melanogaster
• Sequence 2: NP_796111.2
• Gene: Gnal / 14680
• MGIID: 95774
• Length: 448
• Species: Mus musculus
• Alignment Length: 379
• Identity: 261/379 - (68%)
• Similarity: 312/379 - (82%)
• Gaps: 6/379 - (1%)

  Fly    10 KQSDVNSED---SKSQKRRSDAISRQLQKDKQLYRATHRLLLLGAGESGKSTIVKQMRILHVDGF 71
            :|..:.:|:   :|..::.|..|.|.|::.|:..:.||||||||||||||||||||||||||:||
Mouse    73 RQEQLRAEEREAAKEARKVSRGIDRMLREQKRDLQQTHRLLLLGAGESGKSTIVKQMRILHVNGF 137

  Fly    72 SDSEKKQKIDDIKKNIRDAILTITGAMSTLNPPVALEKKENEPRVEYIQDYASSPDFNYPPEFYE 136
            :..||||||.||:||::|||:||..||||:.|||.|...||:.|.:||:..|...||.|..||::
Mouse   138 NPEEKKQKILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSIAPITDFEYSQEFFD 202

  Fly   137 HTEELWKDKGVLQTYERSNEYQLIDCAKYFLDRVSTIKNPNYTPNEQDILRCRVLTSGIFETRFQ 201
            |.::||.|:||...:||||||||||||:|||:|:.::...:|||.:||:||||||||||||||||
Mouse   203 HVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQ 267

  Fly   202 VDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVTACSSYNMVLREDPTQNRLRESLDLFKSIWN 266
            ||||||||||||||||||||||||||||||||:|.||||||||:|||...||||||||||:||||
Mouse   268 VDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRESLDLFESIWN 332

  Fly   267 NRWLRTISIILFLNKQDLLAEKIKAGKSKLSEYFSEFNKYQTPIDTGDAIMESNDDPEVIRAKYF 331
            |||||||||||||||||:||||:.|||||:.:||.|:..|..|   .||..::.:||:|.|||:|
Mouse   333 NRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVP---EDATPDAGEDPKVTRAKFF 394

  Fly   332 IRDEFLRISTASGDGKHYCYPHFTCAVDTENIKRVFNDCRDIIQRMHLRQYELL 385
            |||.|||||||:||||||||||||||||||||:|||||||||||||||:|||||
Mouse   395 IRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLKQYELL 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphas	NP_001163283.1	G-alpha	44..379	CDD:206639	245/334 (73%)
Gnal	NP_796111.2	G_alpha	91..445	CDD:214595	253/356 (71%)
		G-alpha	110..442	CDD:206639	245/334 (73%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	522	1.000	Domainoid score	I301
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	555	1.000	Inparanoid score	I1108
Isobase	1	0.950	-	0.878984	Normalized mean entropy	S897
OMA	1	1.010	-	-		QHG48884
OrthoDB	1	1.010	-	-		D325067at33208
OrthoFinder	1	1.000	-	-		FOG0004018
OrthoInspector	1	1.000	-	-		otm42477
orthoMCL	1	0.900	-	-		OOG6_106085
Panther	1	1.100	-	-	O	PTHR10218
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3262
SonicParanoid	1	1.000	-	-		X2771
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.820