Protein Alignment Galphas and Gna14

DIOPT Version :10

• Sequence 1: NP_477505.1
• Gene: Galphas / 37805
• FlyBaseID: FBgn0001123
• Length: 385
• Species: Drosophila melanogaster
• Sequence 2: NP_032163.3
• Gene: Gna14 / 14675
• MGIID: 95769
• Length: 355
• Species: Mus musculus
• Alignment Length: 381
• Identity: 154/381 - (40%)
• Similarity: 215/381 - (56%)
• Gaps: 44/381 - (11%)

  Fly    16 SEDSKSQKRRSDAISRQLQKDKQLYRATHRLLLLGAGESGKSTIVKQMRILHVDGFSDSEKKQKI 80
            |.:.|..:|.|..|.|||::||:..|...:|||||.|||||||.:|||||:|..|:||.::|...
Mouse     8 SAEEKESQRISAEIERQLRRDKKDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDRKGFT 72

  Fly    81 DDIKKNIRDAILTITGAMSTLNPPVALEK-KEN-----EPRVEYI----QDYASSPDFNYPPEFY 135
            ..:.:||..|:..:..||.||......|: |||     |..|:.:    :|..::
Mouse    73 KLVYQNIFTAMQAMIRAMDTLRIQYMCEQNKENAQIIREVEVDKVTALSRDQVAA---------- 127

  Fly   136 EHTEELWKDKGVLQTYERSNEYQLIDCAKYFLDRVSTIKNPNYTPNEQDILRCRVLTSGIFETRF 200
              .::||.|.|:.:.|:|..||||.|.|||:|..:..|..|::.|.:||:||.||.|:||.|..|
Mouse   128 --IKQLWLDPGIQECYDRRREYQLSDSAKYYLTDIERIAMPSFVPTQQDVLRVRVPTTGIIEYPF 190

  Fly   201 QVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVTACSSYNMVLREDPTQNRLRESLDLFKSIW 265
            .::.:.|.|.||||||.||||||.||..||:|||:.|.|.|:.||.|...:||:.||..||::|.
Mouse   191 DLENIIFRMVDVGGQRSERRKWIHCFESVTSIIFLVALSEYDQVLAECDNENRMEESKALFRTII 255

  Fly   266 NNRWLRTISIILFLNKQDLLAEKIKAGKSKLSEYFSEFNKYQTPIDTGDAIMESNDDPEVIRAKY 330
            ...|....|:||||||:|||.|||.  .|.|..||.|:        ||        ..:.::|
Mouse   256 TYPWFLNSSVILFLNKKDLLEEKIM--YSHLISYFPEY--------TG--------PKQDVKA-- 300

  Fly   331 FIRDEFLRI-STASGDGKHYCYPHFTCAVDTENIKRVFNDCRDIIQRMHLRQYELL 385
             .||..|:: ...:.|.:...|.|||||.|||||:.||...:|.|.:::||::.|:
Mouse   301 -ARDFILKLYQDQNPDKEKVIYSHFTCATDTENIRFVFAAVKDTILQLNLREFNLV 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphas	NP_477505.1	G-alpha	44..379	CDD:206639	140/345 (41%)
Gna14	NP_032163.3	G-alpha	36..349	CDD:206639	140/345 (41%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	37..50		10/12 (83%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	174..182		5/7 (71%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	197..206		6/8 (75%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	266..273		6/6 (100%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	325..330		3/4 (75%)