Protein Alignment Galphas and Gna13

DIOPT Version :9

• Sequence 1: NP_001163283.1
• Gene: Galphas / 37805
• FlyBaseID: FBgn0001123
• Length: 385
• Species: Drosophila melanogaster
• Sequence 2: NP_034433.3
• Gene: Gna13 / 14674
• MGIID: 95768
• Length: 377
• Species: Mus musculus
• Alignment Length: 412
• Identity: 142/412 - (34%)
• Similarity: 204/412 - (49%)
• Gaps: 81/412 - (19%)

  Fly     2 GCFGSPTSKQSDVNSEDSKSQKRRSDAISRQLQKDKQLYRATHRLLLLGAGESGKSTIVKQMRIL 66
            ||          |.:.....|:|:|..|.:.|.::|...:...::||||||||||||.:|||||:
Mouse    17 GC----------VLTNGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRII 71

  Fly    67 HVDGFSDSEKKQKIDDIKKNIRDAILTITGAMSTLNPPVALEKKE-------------------- 111
            |...|....:::....|..|:...:..:..|...|:.|....|.:
Mouse    72 HGQDFDQRAREEFRPTIYSNVIKGMRVLVDAREKLHIPWGDNKNQLHGDKLMAFDTRAPMAAQGM 136

  Fly   112 NEPRVEYIQDYASSPDFNYPPEFYEHTEELWKDKGVLQTYERSNEYQLIDCAKYFLDRVSTIKNP 176
            .|.|| ::|         |.|..    ..||:|.|:...|:|..|:||.:..|||||.:..:..|
Mouse   137 VETRV-FLQ---------YLPAI----RALWEDSGIQNAYDRRREFQLGESVKYFLDNLDKLGVP 187

  Fly   177 NYTPNEQDILRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVTACSSY 241
            :|.|::||||..|..|.||.|..|::..|.|.|.||||||.||::|.:||:.||:|:|:.:.|.:
Mouse   188 DYIPSQQDILLARRPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEF 252

  Fly   242 NMVLREDPTQNRLRESLDLFKSIWNNRWLRTISIILFLNKQDLLAEKIKAGKSKLSEYFSEFNKY 306
            :.||.||...|||.|||::|::|.|||....:||||||||.|||.||::.  ..:.:||.||
Mouse   253 DQVLMEDRQTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQV--VSIKDYFLEF--- 312

  Fly   307 QTPIDTGDAIMESNDDPEVIR--AKYFI-------RDEFLRISTASGDGKHYCYPHFTCAVDTEN 362
                         ..||..:|  .|:.:       ||:..|          ..|.|||.|::|||
Mouse   313 -------------EGDPHCLRDVQKFLVECFRGKRRDQQQR----------PLYHHFTTAINTEN 354

  Fly   363 IKRVFNDCRDIIQRMHLRQYEL 384
            |:.||.|.:|.|...:|:|..|
Mouse   355 IRLVFRDVKDTILHDNLKQLML 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphas	NP_001163283.1	G-alpha	44..379	CDD:206639	130/363 (36%)
Gna13	NP_034433.3	G_alpha	29..375	CDD:214595	137/387 (35%)
		G-alpha	49..371	CDD:206639	130/363 (36%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	50..63		10/12 (83%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	195..203		4/7 (57%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	218..227		6/8 (75%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	287..294		6/6 (100%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	347..352		2/4 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820