DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Galphas and gnat2

DIOPT Version :9

Sequence 1:	NP_001163283.1	Gene:	Galphas / 37805	FlyBaseID:	FBgn0001123	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_001135577.1	Gene:	gnat2 / 100216126	XenbaseID:	XB-GENE-6258657	Length:	354	Species:	Xenopus tropicalis

Alignment Length:	370	Identity:	161/370 - (43%)
Similarity:	222/370 - (60%)	Gaps:	24/370 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 SDVNSEDSKSQKRRSDAISRQLQKDKQLYRATHRLLLLGAGESGKSTIVKQMRILHVDGFSDSEK 76
            |..::|| |...:||..:.::||:|..:...|.:||||||||||||||||||:|:|.||:|:.|.
Frog     3 SGASAED-KELAKRSKELEKKLQEDAAMDAKTVKLLLLGAGESGKSTIVKQMKIIHQDGYSEQEC 66

  Fly    77 KQKIDDIKKNIRDAILTITGAMSTLNPPVALEKKENEPRV-EYIQDYASSPDFNYPPEFYEHTEE 140
            .:....|..||..:||.|..|||||........:.::.|: .::.|  |..:...|.|..:..::
Frog    67 IEFRAIIYGNILQSILAIIRAMSTLGIDYGDSSRADDGRILSHLAD--SIEEGTMPQELVDVIKK 129

  Fly   141 LWKDKGVLQTYERSNEYQLIDCAKYFLDRVSTIKNPNYTPNEQDILRCRVLTSGIFETRFQVDKV 205
            ||||.||...:||:.||||.|.|.|:|:::..|...||.|||||:||.||.|:||.|::|....:
Frog   130 LWKDDGVQACFERAAEYQLNDSAAYYLNQLDRITASNYIPNEQDVLRSRVKTTGIIESQFSFKDL 194

  Fly   206 NFHMFDVGGQRDERRKWIQCFNDVTAIIFVTACSSYNMVLREDPTQNRLRESLDLFKSIWNNRWL 270
            :|.||||||||.||:|||.||..||.|||..|.|:|:|||.||...||:.|||.||.||.|:::.
Frog   195 HFRMFDVGGQRSERKKWIHCFEGVTCIIFCGALSAYDMVLVEDEEVNRMHESLHLFNSICNHKFF 259

  Fly   271 RTISIILFLNKQDLLAEKIKAGKSKLSEYFSEFNKYQTPIDTGDAIMESNDDPEVIRAKYFIRDE 335
            ...||:|||||:||..:|||  |..||..|.:::...|..|.|:                :|:.:
Frog   260 AATSIVLFLNKKDLFEQKIK--KVHLSICFPDYDGPNTFDDAGN----------------YIKQQ 306

  Fly   336 FLRISTASGDGKHYCYPHFTCAVDTENIKRVFNDCRDIIQRMHLR 380
            ||.::... |.|. .|.|.|||.||:|:|.||:...|||.:..|:
Frog   307 FLDLNMRK-DSKE-IYGHMTCATDTQNVKFVFDAVTDIIIKETLK 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Galphas	NP_001163283.1	G-alpha	44..379	CDD:206639	150/335 (45%)
gnat2	NP_001135577.1	G-alpha	34..348	CDD:206639	150/335 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920